Bisphosphonates - xws li alendronate (Fosamax, Binosto), risedronate (Actonel, Atelvia), ibandronate (Boniva) thiab zoledronic acid (Reclast, Zometa) - thiab denosumab (Prolia, Xgeva) tau txuas rau osteonecrosis ntawm lub lub puab tsaig thiab atypical femoral fractures.
Ntau npaum li cas yog osteonecrosis ntawm lub puab tsaig nrog Prolia?
DENVER - Osteonecrosis ntawm lub puab tsaig (ONJ) yog qhov tshwm sim tsis tshua muaj tshwm sim hauv cov poj niam noj denosumab rau kev mob plab tom qab yug me nyuam, nrog rau 0.7% tus nqi rau cov poj niam uas tau tshaj tawm txog qhov ncauj qhov ncauj. lossis cov xwm txheej thaum noj tshuaj thiab 0.05% tus nqi rau cov poj niam uas tsis muaj cov txheej txheem zoo li no, Nelson Watts, MD, qhia ntawm …
Cov teeb meem ntawm lub puab tsaig Prolia ua li cas?
Prolia tuaj yeem ua rau pob txha poob (osteonecrosis) hauv lub puab tsaig. Cov tsos mob muaj xws li mob lub puab tsaig los yog loog loog, cov pos hniav liab los yog o, cov hniav xoob, cov pos hniav, los yog kev kho mob qeeb tom qab kev kho hniav.
Yuav tshuaj twg cuam tshuam nrog osteonecrosis ntawm lub puab tsaig?
Osteonecrosis ntawm lub puab tsaig (ONJ) tuaj yeem tshwm sim los ntawm ob lub chaw muag tshuaj: Antiresorptive (xws li bisphosphonates (BPs)thiab receptor activator ntawm nuclear factor kappa-B ligand [RANK- L] inhibitors) thiab antiangiogenic.
Qhov phom sij ntawm Prolia yog dab tsi?
Cov kev phiv loj ntawm Prolia yog dab tsi?
- pob txha hnyav, pob qij txha, lossis mob leeg.
- kab mob hnyav, suav nrog kab mob urinary loj lossis kab mob ntawm daim tawv nqaij.
- pob txha pob txha pob txha pob txha
- txo cov pob txha tsim (cov pob txha siv sijhawm ntev dua los tsim cov ntaub so ntswg tshiab)
