Txawm hais tias feem ntau hom I membrane-bound proteins muaj teeb liab peptides, feem ntau ntawm hom II thiab ntau-spanning membrane-bound proteins yog tsom mus rau txoj kev secretory los ntawm lawv thawj transmembrane domain, uas biochemically zoo li lub teeb liab sib lawv liag tshwj tsis yog tias
Puas peptides ib txwm tau cleaved?
Lwm qhov txawv txav thiab tseem ceeb ntawm cov proteins hauv nuclear yog tias yuav luag txhua qhov kev ua haujlwm loj ntawm cov molecules tseem muaj lawv cov teeb liab peptides, xws li muaj tsis muaj cleavage ntawm thaj tsam teeb liab no thaum xa mus rau hauv lub nucleus..
Puas yog cov cim qhia ib txwm raug tshem tawm?
Cov cim qhia tsis tau ib txwm pom ntawm cov polypeptides ua tiav hauv cov hlwb, txhais tau hais tias cov teeb liab sib lawv liag yog cleaved los ntawm cov protein thaum nws tseem loj hlob ntawm ribosome.
qhov teeb meem peptidase cleave qhov twg?
Signal peptidases yog cov membrane proteases uas ua lub luag haujlwm tseem ceeb hauv kev thauj cov protein ntawm cov kab mob. Lawv cleave tawm lub teeb liab peptide los ntawm precursor proteins uas yog membrane tso los ntawm SecYEG los yog Tat translocons.
Peptides puas tau txais txiaj ntsig?
Lub teeb liab peptide ntawm PTHrP muaj ntau yam qauv qauv, uas yog evolutionarily zoo-conserved ntawm cov tsiaj tsiaj tab sis tsis zoo rau nws ER lub hom phiaj thiab / lossis kev hloov pauv (Fig.
