Nuclear localization signals tsis raug tshem tawm tom qab thauj mus rau hauv lub nucleus. Qhov no yog qhov xav tau vim nuclear proteins yuav tsum tau xa rov qab, ib zaug tom qab txhua lub cell faib.
Dab tsi yog ob qho laj thawj uas yuav ua rau lub chaw teeb tsa nuclear hauv cheeb tsam NLS tsis raug tshem tawm rau cov proteins nuclear?
Ob txoj kev ua tau zoo suav nrog kev npog NLS xws li nws tsis lees paub los ntawm importin. Qhov npog ntsej muag no tuaj yeem yog: (1) intermolecular, uas lwm cov protein khi thiab ua rau NLS, lossis (2) intramolecular, uas cov protein nws tus kheej folds hauv txoj kev uas lub teeb liab npog.
Puas yog nuclear localization teeb liab cleaved?
Feem ntau, NLS yog qhov ncab ntawm 7-20 amino acids nyob rau hauv cov khoom noj protein. … Feem ntau, NLS yog nplua nuj nyob rau hauv cov amino acids yooj yim, tsis cleaved los ntawm cov protein tom qab ntshuam, thiab ua haujlwm ywj siab ntawm nws txoj hauj lwm nyob rau hauv cov protein molecule.
Vim li cas nws tseem ceeb heev uas cov teeb liab hauv cheeb tsam nuclear tseem txuas nrog cov protein?
Vim li cas nws tseem ceeb heev uas cov teeb liab hauv cheeb tsam nuclear tseem txuas nrog lawv cov protein? … Kuv cov lus teb: NLS yog siv rau ob qho tib si ntshuam thiab xa tawm cov proteins hauv thiab tawm ntawm lub nucleus, yog tias NLS raug tshem tawm (lossis rov xa tawm) cov proteins yuav tsis tshwm sim.
Lub teeb liab hauv cheeb tsam nuclear ua dab tsi?
Nuclear localization signals (NLS) feem ntau yog luv peptides uas ua raws li ib lub teeb liab tawg uas kho cov kev thauj cov protein los ntawm cytoplasm mus rau hauv lub nucleus.
