Unconjugated hyperbilirubinemia tshwm sim nrog nce bilirubin ntau lawm tshwm sim los ntawm kev puas tsuaj ntawm cov ntshav liab, xws li hemolytic ntshawv siab, thiab kev puas tsuaj ntawm bilirubin conjugation, xws li Gilbert syndrome.
Yuav ua li cas feem ntau ua rau tsis sib haum xeeb hyperbilirubinemia?
Hyperbilirubinemia hauv menyuam yaus feem ntau yog tsis sib txuas thiab feem ntau tshwm sim los ntawm teeb meem nrog cov ntshav liab ruaj khov thiab muaj sia nyob lossis los ntawm qhov tsis xws ntawm bilirubin-conjugating enzyme, UGT Hauv qhov sib piv, cov teeb meem uas tshwm sim nyob rau hauv conjugated hyperbilirubinemia feem ntau yog tshwm sim los ntawm intrinsic daim siab dysfunction.
Dab tsi yog qhov ua rau tsis muaj bilirubin?
Unconjugated hyperbilirubinemia tuaj yeem tshwm sim los ntawm nce ntau lawm, impaired conjugation, los yog impaired hepatic uptake ntawm bilirubin, daj daj xim xim uas tsim los ntawm hemoglobin thaum lub sij hawm erythrocyte puas. Nws kuj tseem tuaj yeem tshwm sim hauv cov menyuam yug tshiab.
Tus kab mob twg cuam tshuam nrog kev tsis sib haum xeeb hyperbilirubinemia?
Nyob hauv Crigler-Najjar syndrome, jaundice pom meej thaum yug los lossis me nyuam mos. Mob hnyav hyperbilirubinemia tuaj yeem ua rau muaj tus mob hu ua kernicterus, uas yog ib hom kev puas hlwb ntawm lub hlwb uas tshwm sim los ntawm kev sib txuam ntawm unconjugated bilirubin nyob rau hauv lub hlwb thiab paj hlwb.
Dab tsi yog qhov ua rau pathologic ua rau lub sijhawm ntev tsis sib haum xeeb hyperbilirubinemia?
Ntawm lwm cov kab mob pathological cuam tshuam nrog lub sijhawm ntev hyperbilirubinemia yog kab mob urinary tract (UTI), congenital hypothyroidism thiab hemolysis. Yog li, txoj kev tshawb no tau ua tiav kom paub txog qhov sib txawv ntawm qhov tsis sib xws ntawm tus mob jaundice hauv cov menyuam yug tshiab.
