Glucokinase Glucokinase Glucokinase yog monomeric protein ntawm 465 amino acids thiab molecular hnyav ntawm kwv 50 kD. https://en.wikipedia.org › wiki › Glucokinase
YGlucokinase - Wikipedia
(hexokinase D) yog ib qho monomeric cytoplasmic enzyme pom nyob rau hauv lub siab thiab txiav txiavuas ua haujlwm tswj cov piam thaj hauv cov kabmob no. Glucokinase yog siv thawj kauj ruam ntawm cov metabolism hauv qabzib, thaum lub sijhawm no cov phosphorylation ntawm qabzib los ntawm ATP tsim cov piam thaj-6-phosphate thiab ADP.
YPuas hexokinase tsuas yog hauv daim siab?
Hexokinase D, ib qho isoenzyme pom tsuas yog hauv daim siab, muaj cov khoom tshwj xeeb. … Vim tias hexokinase D kev ua haujlwm tsis cuam tshuam los ntawm qabzib 6-phosphate, qhov enzyme no txhawb nqa lub siab lub peev xwm los tswj cov ntshav qabzib.
Lub luag haujlwm ntawm hexokinase yog dab tsi?
Hexokinase yog thawj enzyme ntawm glycolysis, catalyzing phosphorylation ntawm qabzib los ntawm ATP rau qabzib-6-P Nws yog ib qho ntawm cov enzymes txwv glycolysis. Nws cov dej num poob sai sai raws li lub hnub nyoog ntawm cov qe ntshav liab. … Hexokinase deficiency zoo li tau txais los ua ib qho kev mob autosomal recessive.
YPuas hexokinase pom hauv cytosol?
Hexokinase I thiab II tau pom nyob rau hauv cytosol thiab khi rau mitochondrial membranes; Qhov feem pua ntawm kev ua haujlwm ntawm daim nyias nyias enzyme tau nce nrog qib ntawm kev hloov pauv los ntawm 32% ntawm tag nrho cov haujlwm hauv lub siab ib txwm mus txog 69% hauv cov qog hlwb dedifferentiated.
Yuav ua li cas siv hexokinase?
Hexokinase yog cov enzyme uas catalyzes qhov no phosphoryl-pawg-hloovHexokinase tau dhau mus thiab induced-fit conformational hloov thaum nws khi rau qabzib, uas thaum kawg tiv thaiv hydrolysis ntawm ATP. Nws tseem yog allosterically inhibited los ntawm physiological concentrations ntawm nws cov khoom tam sim ntawd, qabzib-6-phosphate.
