Ua kom lub hlwb hexokinase los ntawm magnesium ionsthiab los ntawm magnesium ion--adenosine triphosphate complex.
Tus activator ntawm hexokinase yog dab tsi?
Cov txiaj ntsig ntawm acidity no tau kov yeej los ntawm cov activators xws li orthophosphate, citrate, malate, 3-phosphoglycerate, thiab riboside triphosphates … Yog li, nyob rau hauv cov kua qaub, ATP tshwm rau ua haujlwm ob qho tib si ua tus activator thiab substrate nrog qhov tshwm sim uas 1 / v piv rau 1 / [ATP] cov phiaj xwm tsis yog linear.
Hexokinase ua haujlwm li cas?
Hexokinase activates glycoloysis los ntawm phosphorylating qabzib… Cov ntaub so ntswg uas muaj hexokinase siv cov piam thaj hauv cov ntshav qis. G6P inhibits hexokinase los ntawm kev khi rau N-terminal domain (qhov no yog kev tawm tswv yim yooj yim inhibition). Nws sib tw inhibits kev khi ntawm ATP [8].
Dab tsi yog cofactor rau cov enzymes hexokinase?
Lub enzyme hexokinase xav tau a magnesium ion ua cofactor.
Vim li cas hexokinase inhibited los ntawm g6p?
Hexokinase, enzyme catalyzing thawj kauj ruam ntawm glycolysis, yog inhibited los ntawm nws cov khoom, qabzib 6-phosphate. … Nyob rau hauv lem, qib ntawm qabzib 6-phosphate nce vim nws nyob rau hauv equilibrium nrogfructose 6-phosphate. Yog li, qhov inhibition ntawm phosphofructokinase ua rau inhibition ntawm hexokinase.
