Kev kuaj pom ntawm neurofibrillary tangles tuaj yeem ua haujlwm ib txwm histological lossis histofluorescent staining txoj kev(xws li, Bielschowsky nyiaj stain lossis thioflavin-S) lossis ntau dua tsis ntev los no immunohistochemical cov tswv yim siv cov tshuaj tiv thaiv kab mob tau raws li qhia hauv Fig.
Koj pom amyloid hauv hlwb li cas?
Ob ntawm qhov tseem ceeb tshaj plaws biomarkers pom nyob rau hauv Alzheimer's yog txo qis cov piam thaj thiab cov pob txha ntawm amyloid plaques hauv lub hlwb. PET scans siv cov tshuaj siv hluav taws xob sib txawv, hu ua radiotracers, los ntsuas cov biomarkers nyob rau hauv lub hlwb cov ntaub so ntswg ntawm cov neeg mob uas tsis txawj ntse.
Ntaus neurofibrillary tangles nyob qhov twg?
Neurofibrillary tangles yog insoluble twisted fibers pom nyob rau hauv lub hlwb lub hlwbCov tangles no muaj feem ntau ntawm cov protein hu ua tau, uas yog ib feem ntawm cov qauv hu ua microtubule. Lub microtubule pab thauj cov as-ham thiab lwm yam tseem ceeb ntawm ib feem ntawm cov paj hlwb mus rau lwm qhov.
Puas tuaj yeem kuaj pom amyloid plaques?
Kev kuaj ntshav tuaj yeem kuaj xyuas seb puas muaj cov plaques ntawm beta-amyloid tsim nyob rau hauv tib neeg lub hlwb - ib qho cim qhia tias lawv tuaj yeem tsim tus kab mob Alzheimer. Cov neeg uas muaj Alzheimer's tus kab mob zoo li yuav muaj cov nplaum nplaum ntawm beta-amyloid hauv lawv lub hlwb, txawm hais tias feem ntawm cov plaques ua si hauv qhov xwm txheej tsis meej.
Cov kev ntsuas twg yog siv los txiav txim siab tus kab mob Alzheimer?
Brain imaging
Ib qho qauv kev kho mob rau Alzheimer's tus kab mob feem ntau suav nrog qauv duab nrog magnetic resonance imaging (MRI) lossis xam tomography (CT)Cov kev sim no feem ntau yog siv los txiav txim rau lwm yam mob uas yuav ua rau cov tsos mob zoo ib yam li Alzheimer's tab sis xav tau kev kho mob sib txawv.
