Vancomycin metabolized nyob qhov twg?

Cov txheej txheem:

Vancomycin metabolized nyob qhov twg?
Vancomycin metabolized nyob qhov twg?

Video: Vancomycin metabolized nyob qhov twg?

Video: Vancomycin metabolized nyob qhov twg?
Video: VANCOMYCIN - What You Need to Know 2024, Hlis ntuj nqeg
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Cov txiaj ntsig tau lees paub tias vancomycin tsis metabolized hauv daim siabthiab feem ntau ntawm vancomycin noj hauv lub cev tau tawm hauv cov zis. Qhov kev poob qis tshaj plaws ntawm vancomycin yog nyob rau hauv nas lub siab microsomes, uas tau degraded 50% nyob rau hauv kwv yees li 6 hnub.

Vancomycin absorbed nyob qhov twg?

Txawm li cas los xij, kev tswj hwm kev siv tshuaj hauv lub cev ntawm vancomycin ua rau lub cev nqus ntawm 54 mus rau 65% ntawm qhov muab tshuaj hauv 6h thiab ua rau cov ntshav kho tau zoo (Pancorbo & Comty, 1982.; Bunke et al., 1983)..

Vancomycin ua haujlwm hauv lub cev li cas?

Vancomycin yog nyob rau hauv ib chav kawm ntawm cov tshuaj hu ua glycopeptide tshuaj tua kab mob. Nws ua haujlwm los ntawm kev tua cov kab mob hauv cov hnyuvVancomycin yuav tsis tua cov kab mob lossis kho cov kab mob hauv lwm qhov ntawm lub cev thaum noj los ntawm qhov ncauj. Cov tshuaj tua kab mob yuav tsis ua haujlwm rau mob khaub thuas, mob khaub thuas, lossis lwm yam kab mob kis.

Vim li cas lub cev ua rau vancomycin cuam tshuam?

Kidney Damage. Vancomycin raug tshem tawm feem ntau hauv lub raum. Feem ntau, vancomycin tuaj yeem ua rau muaj teeb meem rau lub raum xws li mob raum raug mob (AKI).

tshuaj tua kab mob metabolised nyob qhov twg?

Tom qab kev faib tawm hauv cov ntaub so ntswg thiab cov kua dej hauv lub cev, metabolising enzymes hauv lub cev yuav ua rau cov tshuaj tua kab mob degrade. Lub siab yog lub hauv paus tseem ceeb ntawm cov metabolism, txawm tias ib qho nqaij mos tuaj yeem ua rau cov tshuaj metabolise. Los ntawm cov txheej txheem metabolic, cov tshuaj yog inactivated thiab hloov mus rau hauv ib qho yooj yim excreted tshuaj.

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