Hydromorphone feem ntau metabolized los ntawm glucuronidation hauv lub siab, nrog ntau dua 95% ntawm cov tshuaj metabolized rau hydromorphone-3-glucuronide nrog rau me me ntawm 6-hydroxy txo cov metabolites. Tsuas yog ib qho me me ntawm cov koob tshuaj hydromorphone raug tso tawm tsis hloov pauv hauv cov zis.
Dilaudid ua tiav qhov twg?
Dilaudid Metabolized nyob qhov twg? Thaum noj, Dilaudid tau ua tiav los ntawm lub cev thiab siv los thaiv qhov mob hauv lub hlwb. Dilaudid yog metabolized nyob rau hauv tib qhov chaw hauv lub cev raws li feem ntau lwm yam opioids: lub siabNyob ntawd, Dilaudid tau tawg mus rau hauv cov metabolite hu ua hydromorphone-3-glucuronide.
Puas yog Dilaudid muaj cov tshuaj metabolites?
Ob qho tib si morphine thiab hydromorphone (Dlaudid) muaj cov metabolites nquag uas paub tias khaws cia hauv cov ntsiab lus ntawm lub raum tsis txaus. Morphine-6-glucuronide thiab morphine-3-glucuronide yog muab los ntawm morphine, thiab hydromorphone-3-glucuronide los ntawm hydromorphone. Cov metabolites nquag no yog renally excreted
Opiates metabolized nyob qhov twg?
Opioid metabolism tshwm sim feem ntau hauv lub siab, uas tsim cov enzymes rau lub hom phiaj no. Cov enzymes no txhawb nqa 2 hom metabolism: theem 1 metabolism (kev hloov pauv cov tshuaj tiv thaiv) thiab theem 2 cov metabolism (kev sib txuas lus).
Puas opioids metabolized hauv siab?
Opioid metabolism noj qhov chaw feem ntau hauv daim siab, uas tsim cov enzymes rau lub hom phiaj no. Cov enzymes no txhawb nqa 2 hom metabolism: theem 1 metabolism (kev hloov pauv cov tshuaj tiv thaiv) thiab theem 2 metabolism (kev sib txuas lus). Phase 1 metabolism feem ntau yog cov tshuaj rau oxidation lossis hydrolysis.
