Cov txheej txheem:
- Dilaudid ua tiav qhov twg?
- Puas yog Dilaudid muaj cov tshuaj metabolites?
- Opiates metabolized nyob qhov twg?
- Puas opioids metabolized hauv siab?
Video: Dilaudid metabolized nyob qhov twg?
2024 Tus sau: Fiona Howard | [email protected]. Kawg hloov kho: 2024-01-10 06:38
Hydromorphone feem ntau metabolized los ntawm glucuronidation hauv lub siab, nrog ntau dua 95% ntawm cov tshuaj metabolized rau hydromorphone-3-glucuronide nrog rau me me ntawm 6-hydroxy txo cov metabolites. Tsuas yog ib qho me me ntawm cov koob tshuaj hydromorphone raug tso tawm tsis hloov pauv hauv cov zis.
Dilaudid ua tiav qhov twg?
Dilaudid Metabolized nyob qhov twg? Thaum noj, Dilaudid tau ua tiav los ntawm lub cev thiab siv los thaiv qhov mob hauv lub hlwb. Dilaudid yog metabolized nyob rau hauv tib qhov chaw hauv lub cev raws li feem ntau lwm yam opioids: lub siabNyob ntawd, Dilaudid tau tawg mus rau hauv cov metabolite hu ua hydromorphone-3-glucuronide.
Puas yog Dilaudid muaj cov tshuaj metabolites?
Ob qho tib si morphine thiab hydromorphone (Dlaudid) muaj cov metabolites nquag uas paub tias khaws cia hauv cov ntsiab lus ntawm lub raum tsis txaus. Morphine-6-glucuronide thiab morphine-3-glucuronide yog muab los ntawm morphine, thiab hydromorphone-3-glucuronide los ntawm hydromorphone. Cov metabolites nquag no yog renally excreted
Opiates metabolized nyob qhov twg?
Opioid metabolism tshwm sim feem ntau hauv lub siab, uas tsim cov enzymes rau lub hom phiaj no. Cov enzymes no txhawb nqa 2 hom metabolism: theem 1 metabolism (kev hloov pauv cov tshuaj tiv thaiv) thiab theem 2 cov metabolism (kev sib txuas lus).
Puas opioids metabolized hauv siab?
Opioid metabolism noj qhov chaw feem ntau hauv daim siab, uas tsim cov enzymes rau lub hom phiaj no. Cov enzymes no txhawb nqa 2 hom metabolism: theem 1 metabolism (kev hloov pauv cov tshuaj tiv thaiv) thiab theem 2 metabolism (kev sib txuas lus). Phase 1 metabolism feem ntau yog cov tshuaj rau oxidation lossis hydrolysis.
Pom zoo:
Qhov twg yog tshuaj tiv thaiv kab mob metabolized?
Cov metabolism ntawm quetiapine tshwm sim ntawm txoj kab siab, feem ntau yog los ntawm CYP3A4 isoenzyme hauv cytochrome P450 thiab kev tso tawm tshwm sim feem ntau ntawm lub raum txoj kev, nrog rau feem pua ntawm kwv yees li 20% yog tawm los ntawm faeces (DeVane thiab Nemeroff, 2001;
Qhov twg yog qhov mob thiab qhov twg yog qhov ceeb?
Panic (lub suab los ntawm Matt Frewer) yog lub ntsej muag ntsuab-xiav nrog lub cev ntev. Thaum nws yog me ntsis cunning dua Pain, nws paranoia txhais tau hais tias nws yog heev ceev faj thiab ntau cynical nyob rau hauv lub sij hawm, yog li nws tej zaum yuav ntse dua ib tug ntawm ob.
Cov ntsia liaj qhov rooj nyob rau hauv qhov phem 3 nyob qhov twg?
Tus Neeg Siab Phem 3 tus ntsia liaj qhov rooj tau pom nyob rau hauv chav me me tsis muaj npe txuas nrog lub Chaw nres tsheb hauv plawv nroog . Kuv puas yuav tsum muab cov ntsia hlau txiav Resident Evil 3? Koj tsis tuaj yeem pov tseg cov khoom koj xav tau rau lub hom phiaj, xws li lub xauv xauv lossis ntsia liaj qhov rooj.
Vancomycin metabolized nyob qhov twg?
Cov txiaj ntsig tau lees paub tias vancomycin tsis metabolized hauv daim siabthiab feem ntau ntawm vancomycin noj hauv lub cev tau tawm hauv cov zis. Qhov kev poob qis tshaj plaws ntawm vancomycin yog nyob rau hauv nas lub siab microsomes, uas tau degraded 50% nyob rau hauv kwv yees li 6 hnub .
Qhov twg yog coumadin metabolized?
Kev tshem tawm ntawm warfarin yuav luag tag nrho los ntawm cov metabolism. COUMADIN yog stereoselectively metabolized los ntawm hepatic microsomal enzymes(cytochrome P-450) rau inactive hydroxylated metabolites (feem ntau txoj kev) thiab los ntawm reductases kom txo cov metabolites (warfarin alcohols) .
