Depolarizing nqaij relaxants ua as ACh receptor agonists Lawv khi rau ACh receptors thiab tsim kom muaj peev xwm ua tau. Txawm li cas los xij, vim tias lawv tsis metabolized los ntawm acetylcholinesterase, kev khi ntawm cov tshuaj no rau cov receptor yog ntev ua rau muaj kev ncua ntev ntawm cov leeg nqaij kawg-phaj.
Dab tsi yog Depolarising nqaij so?
Depolarizing nqaij relaxants ua raws li acetylcholine (ACh) receptor agonists los ntawm kev khi rau ACh receptors ntawm lub tshuab kawg ntawm lub cev thiab tsim kom muaj peev xwm ua tau.
Suxamethonium ua rau cov leeg so li cas?
As cov calcium tau txais los ntawm sarcoplasmic reticulum, cov leeg nqaij so. Qhov no piav qhia txog cov leeg nqaij flaccidity ntau dua li tetany tom qab fasciculations. Cov txiaj ntsig tau yog daim nyias nyias depolarization thiab fasciculations ib ntus, ua raws li kev tuag tes tuag taw.
Succinylcholine ua rau cov leeg nqaij so li cas?
Succinylcholine yog ib qho depolarizing skeletal leeg relaxant. Raws li acetylcholine, nws ua ke nrog cholinergic receptors ntawm lub tshuab kawg phaj los tsim depolarization. Qhov no depolarization yuav raug pom raws li fasciculations.
NMJ blockers ua dab tsi?
Lub depolarizing NMBA ua rau cov receptors ntawm lub tshuab kawg ntawm cov hlab ntsha neuromuscular hlws ris (NMJ), ua rau depolarizing ntawm daim nyias nyias. Qhov kev txiav txim no ua rau lub cev muaj zog endplate refractory rau qhov kev txiav txim ntawm ACh. Ib qho piv txwv ntawm non-depolarizing NMBA yog succinylcholine.
