Depolarizing nqaij relaxants ua as ACh receptor agonists Lawv khi rau ACh receptors thiab tsim kom muaj peev xwm ua tau. Txawm li cas los xij, vim tias lawv tsis metabolized los ntawm acetylcholinesterase, kev khi ntawm cov tshuaj no rau cov receptor yog ntev ua rau muaj kev ncua ntev ntawm cov leeg nqaij kawg-phaj.
Yuav ua li cas depolarizing neuromuscular blockers ua haujlwm?
Depolarizing agents Depolarizing agents tsim lawv cov block by binding to and activating the ACh receptor, at first makes muscle contraction, then paralysis. Lawv khi rau cov receptor thiab ua rau depolarization los ntawm kev qhib cov channel ib yam li acetylcholine ua.
Cov tshuaj depolarizing thiab tsis depolarizing cov leeg nqaij so ua haujlwm li cas?
Neuromuscular blockade tshwm sim txawm tias tsuas yog ib qho α subunit raug thaiv. Yog li, depolarizing nqaij relaxants ua raws li ACh receptor agonists, whereas nondepolarizing nqaij relaxants ua hauj lwm raws li kev sib tw antagonists Qhov sib txawv ntawm cov txheej txheem ntawm kev txiav txim piav qhia lawv cov teebmeem sib txawv hauv qee lub xeev.
Succinylcholine ua rau cov leeg so li cas?
QUESTION. Succinylcholine yog ib qho depolarizing skeletal leeg relaxant. Raws li acetylcholine, nws ua ke nrog cov cholinergic receptors ntawm lub tshuab kawg phaj los tsim depolarization. Qhov no depolarization yuav raug soj ntsuam raws li fasciculations.
Yuav ua li cas cov leeg nqaij so ua haujlwm hauv Anaesthesia?
Neuromuscular thaiv cov tshuaj siv tshuaj loog kuj hu ua cov leeg nqaij so. Los ntawm tshwj xeeb thaiv ntawm cov kab mob neuromuscular hlws rislawv ua kom lub teeb tshuaj loog siv nrog kev so txaus ntawm cov leeg nqaij ntawm lub plab thiab diaphragm. Lawv kuj so lub suab qaum thiab tso cai rau txoj hauv kev ntawm txoj hlab pas.
