Puas yog ib qho tseem ceeb ntawm cov tshuaj lom neeg lom neeg ntawm thiols?

2024 Tus sau: Fiona Howard | [email protected]. Kawg hloov kho: 2024-01-10 06:38

Dab tsi ntawm cov hauv qab no yog qhov tseem ceeb ntawm cov tshuaj lom neeg lom neeg ntawm thiols? kev oxidation ntawm ob thiols los ua ib tug disulfide.

Yam thiols yog dab tsi?

1 BIOLOGICAL THIOLS

Thiols xa mus rau chav kawm ntawm cov organic sulfur derivatives uas yog tus cwj pwm los ntawm qhov muaj sulfhydryl residues (–SH) ntawm lawv qhov chaw nquagTshuaj, thiols yog mercaptans (C-SH) thiab biological mercaptans feem ntau hu ua biological thiols lossis biothiols [1].

Yuav ua li cas yog qhov tseem ceeb ntawm thiols?

Thiols pabcuam lub luag haujlwm tseem ceeb hauv cov protein-based thiab qis-molecular-yuag redox systems Thiol-based antioxidants tiv thaiv kab mob tiv thaiv oxidative kev nyuaj siab. Thiols hauv antioxidant enzymes tuaj yeem xa cov cim oxidative rau lwm cov proteins. Glutathione sawv cev rau qhov sib npaug sib npaug ntawm qhov tshwj xeeb txo nyiaj.

Yuav ua li cas thiols raug?

Cov pab pawg thiol hauv Cys tuaj yeem nkag mus oxidation cov tshuaj tiv thaiv tsim sulfenic (R-S-OH), sulfinic (R-SO ₂ H), thiab sulfonic (R-SO_{3H) derivatives as well as the disulfide bond.}

Yuav ua li cas thiols tsim?

Thiols tuaj yeem tsim los ntawm haloalkanes los ntawm nucleophilic hloov pauv ntawm halide ion los ntawm sulfhydryl ion (HS ^{-), uas yog ib qho zoo heev nucleophile. Vim tias thiolate ions kuj tseem zoo heev nucleophiles, thioethers tuaj yeem hnov qab rov muab thioether.}