Megaloblastic anemia yog ib qho mob uas cov pob txha pob txha tsim cov pob txha loj heev, cov txheej txheem txawv txav, cov qe ntshav liab tsis paub meej(megaloblasts). Cov pob txha pob txha, cov ntaub mos mos uas pom hauv cov pob txha, tsim cov qe ntshav tseem ceeb ntawm lub cev - cov qe ntshav liab, hlwb dawb, thiab platelets.
Vim li cas thiaj hu ua megaloblastic anemia?
Megaloblastic anemia yog tus cwj pwm los ntawm RBCs uas loj dua li ib txwmTseem tsis txaus ntawm lawv. Thaum RBCs tsis tsim kom raug, nws ua rau megaloblastic anemia. Vim tias cov qe ntshav loj dhau lawm, lawv yuav tsis tuaj yeem tawm hauv cov pob txha mus rau hauv cov hlab ntsha thiab xa oxygen.
Qhov twg ntawm qhov tsis txaus ua rau megaloblastic anemia?
Yog tsis muaj oxygen txaus, koj lub cev ua haujlwm tsis tau zoo. Folic acid tseem hu ua folate. Nws yog lwm cov vitamin B. Txawm li cas los xij tsis muaj vitamin B-12 lossis tsis muaj folate ua rau hom ntshav qab zib hu ua megaloblastic anemia (pernicious anemia).
Megaloblastic vs non megaloblastic yog dab tsi?
Megaloblasts yog cov qe ntshav liab loj (RBC) precursors nrog noncondensed chromatin vim tsis muaj DNA synthesis. Macrocytes yog enlarged RBCs (ie, txhais tau tias corpuscular ntim [MCV] > 100 fL / cell). Macrocytic RBCs tshwm sim nyob rau hauv ntau qhov chaw kho mob, ntau yam tsis cuam tshuam rau megaloblastic maturation.
Dab tsi ua rau megaloblastic macrocytic anemia?
Qhov feem ntau ua rau megaloblastic, macrocytic anemia yog deficiency lossis siv tsis zoo ntawm vitamin B12 lossis folateUa tiav cov ntshav suav, ntsuas ntshav liab, ntsuas reticulocyte, thiab peripheral smear. Ntsuas vitamin B12 thiab folate qib thiab xav txog kev kuaj methylmalonic acid thiab homocysteine kev kuaj.
