Los ntawm kev hloov cov roj (cholesterol) mus rau cov roj cholesterol esters cov roj cholesterol esters Cov roj cholesterol ester, cov lipid noj zaub mov, yog tus ester ntawm cov roj cholesterol ester daim ntawv cog lus yog tsim los ntawm pawg carboxylate ntawm fatty acid thiab hydroxyl pawg ntawm cov cholesterol. Cov roj (cholesterol) esters muaj qis solubility hauv dej vim lawv cov hydrophobicity ntau dua. https://en.wikipedia.org › wiki › Cholesteryl_ester
Cholesteryl ester - Wikipedia
ntau cov roj cholesterol tuaj yeem ntim rau hauv cov lipoproteins sab hauv. Qhov no ua rau kom muaj peev xwm ntawm lipoproteins ntau, ua rau kom muaj txiaj ntsig zoo ntawm cov roj cholesterol hauv cov hlab ntsha.
Vim li cas cov roj cholesterol esterified hauv HDL?
Cov khoom uas muaj peev xwm ua rau cov roj cholesterol ntawm tes yog tsim los ntawm cov txheej txheem no. Yog li, qhov ua tau zoo ntawm cov roj cholesterol esterification / hloov pauv thiab hloov kho HDL yuav txhim kho cov roj cholesterol rov qab thiab txo qhov kev pheej hmoo rau cov kab mob plawv.
Cov roj cholesterol esterified li cas?
Cellular cholesterol esterification yog ua tiav los ntawm ob lub enzymes: ACAT1, uas yog dav faib, tab sis qhia qis qis hauv daim siab thiab cov hnyuv; thiab ACAT2, uas yog lub luag haujlwm rau cov roj cholesterol esterification hauv cov ntaub so ntswg (69).
Lub ntsiab lus ntawm cov roj cholesterol esterification yog dab tsi?
Cholesteryl ester, ib qho noj lipid, yog ester ntawm cov roj cholesterol. Cov ester daim ntawv cog lus yog tsim los ntawm pawg carboxylate ntawm fatty acid thiab pawg hydroxyl ntawm cov cholesterol..
Qhov twg esterified cov cholesterol pom hauv cov hlwb?
Hauv cov hlwb, tom qab qhov pib theem ntawm cov roj cholesterol hauv cellular tau mus txog, cov roj cholesterol ntau dhau yog esterified hauv the ERlos ntawm enzyme acyl CoA cholesterol acyltransferase (ACAT), thiab cov CEs tshiab tau muab khaws cia rau hauv cov lipid droplets.