Hypochlorhydria lossis achlorhydria feem ntau yog vim cov nyhuv inhibitory ntawm parietal hlwb ntawm parietal mucosa, ua rau txo qis gastric acid ntau lawm (16). Qhov no feem ntau ua rau malabsorption ntawm qhov tseem ceeb electrolytes thiab vitamins.
Vim li cas VIPoma ua rau mob raws plab?
VIP yog 28 amino acid polypeptide uas khi rau siab affinity receptors ntawm plab hnyuv epithelial hlwb, ua rau kom cov cellular adenylate cyclase thiab cAMP ntau lawm. Qhov no ua rau net kua thiab electrolyte tso rau hauv lub lumen, ua rau secretory raws plab thiab hypokalemia [6, 7].
Vim li cas VIPoma ua rau hypercalcemia?
Hypercalcemia tuaj yeem cuam tshuam nrog VIPomas. Ntawm cov neeg mob VIPoma nrog hypercalcemia, txog li 5% muaj kho tau hyperparathyroidism cuam tshuam nrog txiv neej-1. Cov qib calcium uas pom nrog hyperparathyroidism feem ntau yog nyob rau hauv thaj tsam me me ntawm 10.5 txog 11 mg / dL [5].
Puas VIPoma ua rau metabolic acidosis?
Cov tsos mob tseem ceeb ntawm vipoma yog lub sijhawm ntev ntawm cov dej raws plab loj (ceev quav ntim > 750 txog 1000 mL / hnub thiab cov ntim tsis yoo mov ntawm > 3000 mL / hnub) thiab cov tsos mob ntawm hypokalemia,metabolic acidosis.
Puas VIPoma ua rau dej ntws?
Kwv yees li 50–75% ntawm VIPomas yog qhov tsis zoo, tab sis txawm tias thaum lawv tsis zoo, lawv muaj teeb meem vim tias lawv nyiam ua rau muaj cov tsos mob tshwj xeeb: VIP ntau ntau ua rau mob plab thiab mob raws plab thiab tshwm sim. Lub cev qhuav dej, hypokalemia, achlorhydria, acidosis, flushing thiab hypotension (los ntawm …
