Antibody drug conjugates (ADCs) yog ib hom tshuaj tiv thaiv kab mob. Lawv yog tsim los ntawm peb yam: monoclonal antibody (mAb) thiab cytotoxic payload ua los ntawm cov kws khomob kws khomob, uas txuas nrog ua ke siv cov tshuaj sib txuas.
Puas yog tshuaj tiv thaiv kab mob tib yam li kev tiv thaiv kab mob?
Tshuaj xyuas los ntawm: Rony Dahan, Ph. D. Lub hom phiaj cov tshuaj tiv thaiv yog ib hom kev kho mob qog noj ntshav uas tuaj yeem cuam tshuam cov qog nqaij hlav qog noj ntshav thiab ceeb toom rau lub cev tiv thaiv kab mob rau lub hom phiaj thiab tshem tawm cov qog nqaij hlav cancer.
Puas yog cov tshuaj tiv thaiv kab mob sib txuas tau suav tias yog kws khomob?
Antibody-drug conjugates lossis ADCs yog ib chav kawm ntawm cov tshuaj biopharmaceutical tsim los ua kev kho mob rau kho mob qog noj ntshav. Tsis zoo li cov kws khomob, ADCs yog npaj los tua cov qog hlwb thaum sparing cov hlwb noj qab haus huv.
Puas yog monoclonal antibody yog kev tiv thaiv kab mob?
Ntau cov tshuaj tiv thaiv monoclonal yog siv los kho mob qog noj ntshav. Lawv yog hom phiaj kho mob qog noj ntshav, uas txhais tau hais tias lawv tau tsim los cuam tshuam nrog cov hom phiaj tshwj xeeb. Kawm paub ntau ntxiv txog kev kho mob. Qee cov tshuaj tiv thaiv kab mob monoclonal tseem yog immunotherapy vim tias lawv pab tig lub cev tiv thaiv kab mob qog noj ntshav
Cov tshuaj tiv thaiv kab mob sib txuas ua haujlwm li cas?
Antibody-Drug Conjugates (ADCs) yog ib chav kawm tshiab ntawm cov tshuaj lom neeg muaj zog uas tsim los ntawm txuas cov tshuaj tiv thaiv kab mob me me lossis lwm tus neeg kho mob rau cov tshuaj tiv thaiv kab mob, nrog rau ib qho mus tas li los yog labile linker. Cov tshuaj tiv thaiv kab mob tsom rau cov tshuaj tiv thaiv tshwj xeeb tsuas yog pom ntawm lub hom phiaj xwb.
36 cov lus nug ntsig txog pom
