Genomic imprinting yog ib qho tshwm sim ntawm epigenetic uas ua rau cov noob tau qhia nyob rau hauv niam txiv-ntawm-cov hauv paus chiv keeb. Genes txawm li cas los xij, kuj tuaj yeem luam tawm ib nrab.
Yeeb imprinted li cas?
Nyob rau hauv genomic imprinting lub peev xwm ntawm ib tug noob yuav tsum tau qhia nyob rau hauv cov poj niam txiv neej uas dhau ntawm cov noob. Qee zaum imprinted genes yog qhia thaum cov tau txais los ntawm leej niam. Lwm qhov xwm txheej lawv tau hais thaum tau txais los ntawm leej txiv.
Puas yog ib tug imprinted noob muab tua?
Imprinting in Somatic Cells
Tshwj xeeb, thaum lub gene ntawm ib tug niam tsev imprinted locus yog qhia, daim ntawv luam ntawm cov imprinted noob los ntawm leej niam yog ib txwm muab "tawm, "the the copy from the father is always turn "on."Qhov txawv yog qhov tseeb ntawm niam txiv imprinted noob.
Puas tib neeg puas muaj cov tshuaj imprinted?
Kwv yees li 150 cov noob imprinted (IGs) paub nyob rau hauv nas thiab ze rau 100 hauv tib neegQee tus ntawm lawv tau txheeb xyuas raws li cov qauv molecular ntawm chromosomal rearrangements lossis uniparental disomies ua rau kev kho mob. Cov tsos mob (Prader-Willi syndrome thiab Beckwith-Wiedemann syndrome, piv txwv li).
Yuav ua li cas yog qhov tshwm sim ntawm cov noob imprinted?
Raws li koj xav tau, nws yog qhov ua tau rau cov kab mob tshwm sim vim kev tshem tawm lossis hloov pauv hauv cov noob caj noob ces. Cov kab mob kuj tuaj yeem tshwm sim los ntawm kev tsis sib haum xeeb, lossis keeb kwm ntawm ob daim ntawv theej ntawm chromosome los ntawm ib tus niam txiv thiab tsis muaj daim ntawv los ntawm lwm tus niam txiv, thaum cov noob cuam tshuam tau luam tawm.
