Nws tau lees paub dav tias tsis yog-enzymatic glycation hauv ntshav qab zib yog qhov ua rau muaj kev puas tsuaj thiab ua haujlwm tsis zoo ntawm cov hlab ntsha tseem ceeb. MG (methylglyoxal) yog tshuaj lom ncaj qha rau cov ntaub so ntswg, thiab yog ib qho tseem ceeb ntawm AGEs (advanced glycation end-products).
Puas methylglyoxal ua rau ntshav qab zib?
Nyob rau hauv cov mob hyperglycemic, intracellularly tsim α-ketoaldehydes, xws li methylglyoxal, yog qhov tseem ceeb ntawm AGEs intracellular, thiab qhov txawv txav ntawm methylglyoxal cuam tshuam nrog txhim kho cov teeb meem ntshav qab zib hauv ntau yam ntaub so ntswg thiab lub cev.
Cov txiaj ntsig ntawm methylglyoxal yog dab tsi?
Methylglyoxal yog nws cov khoom xyaw nquag thiab yuav muaj lub luag haujlwm rau cov tshuaj tiv thaiv kab mob Tsis tas li ntawd, manuka zib ntab muaj cov tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob antioxidant. Qhov tseeb, nws tau ib txwm siv los kho qhov txhab, soothing caj pas, tiv thaiv cov hniav lwj thiab txhim kho digestive teeb meem.
YPuas yog methylglyoxal phem?
Qhov sib txuam ntawm cov cell-permeant MG yog qhov tsis zoo, vim tias qhov sib xyaw no yog ib qho muaj zog tshaj plaws glycating cov neeg ua haujlwm tsim tawm hauv cov hlwb. Nws nkag siab nrog cov proteins, lipids thiab nucleic acids los tsim cov khoom siv glycation kawg (AGEs).
Vim li cas methylglyoxal toxic?
Qhov sib txuam ntawm cov cell-permeant MG yog hnyav heev, vim tias qhov sib xyaw no yog ib qho ntawm cov muaj zog tshaj glycating cov neeg ua haujlwm tsim tawm hauv cov hlwb. Nws nkag siab nrog cov proteins, lipids thiab nucleic acids los tsim cov khoom siv glycation kawg (AGEs).