Fatty acids thiab ketogenic amino acids tsis tuaj yeem siv los ua ke cov piam thaj. Cov tshuaj tiv thaiv kev hloov pauv yog ib txoj kev tshuaj tiv thaiv, txhais tau hais tias acetyl-CoA tsis tuaj yeem hloov rov qab mus rau pyruvate Vim li ntawd, fatty acids tsis tuaj yeem siv los tsim cov piam thaj, vim tias beta-oxidation. tsim acetyl-CoA.
Puas yog acetyl-CoA ua ntej rau gluconeogenesis?
Acetyl-CoA yog qhov taw qhia ntawm cov cell metabolic kev ua haujlwm thiab ua haujlwm raws li gluconeogenesis regulator ntawm ib cheeb tsam. Acetyl-CoA qib rov qab thiab allosterically qhib pyruvate carboxylase. Ua li no, lub xov tooj ntawm tes ua kom ntseeg tau tias gluconeogenesis thiab TCA lub voj voog yuav tsis tshwm sim ib txhij.
Puas yog acetyl-CoA ua ntej?
Acetyl CoA yog ua ntej rau kev sib txuas ntawm fatty acidsAcetyl CoA yog muab ntau txoj hauv kev. … Ib qho ua tau yog tias nws tsim nyob rau hauv mitochondria los ntawm hydrolysis ntawm acetyl CoA, uas tau los ntawm oxidation ntawm pyruvate los ntawm mitochondrial pyruvate dehydrogenase complex.
Qhov twg hauv qab no tsis yog qhov ua ntej ntawm gluconeogenesis?
Dab tsi ntawm cov hauv qab no tsis yog qhov ua ntej ntawm gluconeogenesis? Kev piav qhia: Tsuas yog leucine lossis lysineyog cov substrate uas tsis yog siv rau gluconeogenesis vim cov amino acids tsim cov acetyl-CoA nkaus xwb thaum degradation. Tsiaj txhu tsis tuaj yeem nqa tawm gluconeogenesis los ntawm ob acetyl carbon ntawm acetyl-CoA.
Yuav ua li cas cov amino acid tuaj yeem siv los ua cov tshuaj gluconeogenic precursor?
YGluconeogenesis. Lub hom phiaj tseem ceeb ntawm cov protein catabolism thaum lub xeev tshaib plab yog los muab cov glucogenic amino acids (tshwj xeeb yog
alanine thiab glutamine ) uas ua haujlwm ua cov substrates rau endogenous qabzib ntau lawm (gluconeogenesis) hauv daim siab.
