Estrogens yog tsim los ntawm kev ua ntawm aromatase, uas hloov testosterone rau estradiol thiab androstenedione rau estrone estrone Lub npe estrone tau muab los ntawm cov ntsiab lus tshuaj estrin (estra-1, 3, 5 (10)-triene) thiab ketone. Cov tshuaj formula ntawm estrone yog C 18 H 22O2thiab nws qhov hnyav molecular yog 270.366 g / mol. Nws yog xim dawb, tsis muaj ntxhiab tsw, cov hmoov crystalline hmoov, nrog lub melting point ntawm 254.5 ° C (490 ° F) thiab lub ntiajteb txawj nqus ntawm 1.23. https://en.wikipedia.org › wiki › Estrone
Estrone - Wikipedia
aromatase ua dab tsi hauv lub cev?
Aromatase yog ib qho enzyme uas hloov androgens rau hauv estrogens, thiab aromatase inhibitors (AIs) tuaj yeem tshem tawm cov tshuaj estrogen.
Dab tsi yog hloov mus rau estrogen los ntawm kev ua haujlwm aromatase?
Aromatase Deficiency
Aromatase yog ib qho cytochrome P450 enzyme uas catalyzes ib kauj ruam tseem ceeb hauv kev hloov pauv ntawm androgens (C19 steroids) rau estrogens (C18 steroids).
Puas siab testosterone hloov mus rau estrogen?
Raws li cov kws sau ntawv tshawb fawb, ib feem me me ntawm testosterone ua los ntawm cov txiv neej feem ntau hloov mus rau hauv estrogen los ntawm aromatase - hom enzyme. Qhov siab dua testosterone qib hauv ib tug txiv neej, ntau testosterone hloov mus ua estrogen.
Dab tsi tiv thaiv testosterone los ntawm kev hloov mus rau estrogen?
Anastrozole yog ib qho tshuaj aromatase-inhibiting uas tuaj nyob rau hauv daim ntawv ntawm ib ntsiav tshuaj thiab noj qhov ncauj. Nws inhibits lub peev xwm ntawm aromatase enzyme los hloov testosterone rau estrogen. Yog li, nws txo qis theem ntawm estradiol circulating zoo heev.
