Cov txheej txheem:
- Kev hloov pauv ntawm epigenetic hloov pauv cov kev qhia gene?
- Kev sib raug zoo ntawm DNA thiab epigenetics yog dab tsi?
- Yuav ua li cas hloov pauv ntawm epigenetic tuaj yeem tshwm sim hauv genome los cuam tshuam cov noob qhia?
- Dab tsi yog epigenetic qhia?
Video: Puas muaj kev hloov pauv ntawm epigenetic cuam tshuam rau dna qhia?
2024 Tus sau: Fiona Howard | [email protected]. Kawg hloov kho: 2024-01-10 06:38
Thaum cov kev hloov caj ces tuaj yeem hloov pauv cov protein uas tsim los, kev hloov pauv ntawm cov noob caj noob ces cuam tshuam rau cov noob caj noob ces tig cov noob "rau" thiab "tawm " Txij li thaum koj ib puag ncig thiab kev coj cwj pwm, xws li kev noj haus thiab kev tawm dag zog, tuaj yeem ua rau muaj kev hloov pauv hauv epigenetic, nws yooj yim pom kev sib txuas ntawm koj cov noob thiab koj tus cwj pwm thiab ib puag ncig.
Kev hloov pauv ntawm epigenetic hloov pauv cov kev qhia gene?
Hnub, kev hloov pauv ntawm epigenetic, lossis "tags," xws li DNA methylation thiab hloov kho histone, hloov DNA nkag tau thiab cov qauv chromatin, yog li tswj cov qauv ntawm cov noob qhia. Cov txheej txheem no tseem ceeb heev rau kev loj hlob ib txwm thiab kev sib txawv ntawm cov kab mob sib txawv ntawm cov kab mob hauv cov neeg laus.
Kev sib raug zoo ntawm DNA thiab epigenetics yog dab tsi?
Epigenetics txhais tau tias "saum toj" lossis "nyob rau saum" caj ces. Nws hais txog kev hloov kho sab nraud rau DNA uas tig cov noob "rau" lossis "tawm." Cov kev hloov kho no tsis hloov DNA ib ntus, tab sis hloov, lawv cuam tshuam li cas cov hlwb "nyeem" noob. Epigenetic hloov pauv hloov lub cev qauv ntawm DNA.
Yuav ua li cas hloov pauv ntawm epigenetic tuaj yeem tshwm sim hauv genome los cuam tshuam cov noob qhia?
Muaj ob hom kev hloov pauv ntawm epigenetic - DNA methylation thiab histone hloov kho (16).
Dab tsi yog epigenetic qhia?
Epigenetics yog txoj kev tshawb fawb ntawm cov hlwb li cas tswj cov noob caj ces yam tsis hloov DNA ua ntu zus. … Nyob rau hauv tag nrho cov DNA nyob rau hauv ib lub xovtooj ntawm tes (genome), tag nrho cov kev hloov kho uas tswj cov kev ua (qhia) ntawm cov noob yog hu ua lub epigenome.
Pom zoo:
Yuav kuaj li cas rau kev hloov pauv ntawm epigenetic?
Ib qho ntawm cov txheej txheem tseem ceeb tshaj plaws los ntsuas cov kev hloov pauv ntawm genome-wide epigenetic yog qhov kev ntsuas ntawm Chip uas siv cov txheej txheem Chip ib txwm siv nrog kev tshuaj ntsuam microarray [22]. Ntxiv nrog rau ChiP, muaj ntau lwm qhov kev ntsuam xyuas uas tuaj yeem siv los ntsuas cov qauv chromatin .
Cuam tshuam lossis cuam tshuam li cas cuam tshuam kev sib txuas lus?
Txhua zaus peb tham lossis mloog, muaj tej yam uas nkag mus rau hauv txoj kev sib txuas lus meej-yam uas cuam tshuam rau tus neeg txais tau cov lus los ntawm tus xa. Qhov kev cuam tshuam no yog hu ua " noise," thiab muaj ntau hom suab nrov uas tuaj yeem ua rau cov lus raug txhais tsis raug .
Puas muaj kev hloov pauv thoob ntiaj teb cuam tshuam ntau dua kev tsiv teb tsaws chaw?
Ntiaj teb no kuj tau nce kev lag luam tsis sib xws ntawm cov teb chaws. Qee cov kws tshawb fawb thiab cov kws tshawb fawb tau sib cav tias kev lag luam thoob ntiaj teb kuj txo qis kev tsiv teb tsaws Kev loj hlob hauv kev lag luam tuaj yeem txo qis kev tsiv teb tsaws los ntawm kev tsim cov hauj lwm ntxiv thiab kev loj hlob ntau dua hauv cov teb chaws xa neeg ua haujlwm .
Puas tsis muaj kev hloov pauv cuam tshuam rau phenotype?
Qhov kev ua haujlwm hauv vitro kev soj ntsuam kev ntxub ntxaug ntawm cov kab mob CDH1 tsis muaj kev hloov pauv (ua rau cov cell adhesion thiab ua rau muaj kev cuam tshuam) thiab cov uas tsis cuam tshuam rau phenotype . Kev hloov pauv dab tsi cuam tshuam rau phenotype?
Puas muaj kev cuam tshuam suav rau ntawm kev hloov pauv ob lub ntsiab lus?
No, interceptions tsis suav rau ib tug 2 point conversion, txhais tau tias kev sim ua tsis tau tab sis txawm tias qhov tshwm sim ntawm kev ua si yog kev cuam tshuam, tsis muaj interception yog sau rau hauv official txheeb cais. … Yog vim li cas qhov no yog 2 taw tes hloov dua siab tshiab yog suav tias yog ib qho taw tes tom qab sim, lossis PAT, thiab tsis yog ib txwm ua si .
