Cov txheej txheem:
- Puas yog digoxin tshem tawm ntawm daim siab?
- Dogoxin tawg li cas?
- Dab tsi enzyme metabolizes digoxin?
- CYP2C19 inhibitors yog dab tsi?
Video: Digoxin metabolised nyob qhov twg?
2024 Tus sau: Fiona Howard | [email protected]. Kawg hloov kho: 2024-01-10 06:38
Txoj hauv kev tseem ceeb ntawm kev tshem tawm yog raum tso tawm ntawm digoxin, uas yog sib raug zoo nrog cov glomerular pom tus nqi. Tsis tas li ntawd, qee qhov tubular secretion thiab tej zaum tubular reabsorption tshwm sim. Yuav luag tag nrho cov digoxin nyob rau hauv cov zis yog tawm tsis hloov, nrog ib feem me me raws li active metabolites.
Puas yog digoxin tshem tawm ntawm daim siab?
Nyob rau hauv xaus, hydrolysis ntawm digitoxin yog hloov pauv hauv daim siab cirrhosis, uas yog qhov txo qis hauv lub raum tshem tawm thiab tso zis rov qab ntawm digitoxigenin-mono-digitoxoside thiab digitoxigenin tau pom nyob rau hauv kev kawm tam sim no.
Dogoxin tawg li cas?
Nyob hauv lub cev, lub ntsiab lus tseem ceeb Digoxin (daim duab saum toj no) tau tawg (tawg ntawm glycosidic bonds) rau Digitoxin thiab qab zib. Cov digitoxin txhawb lub plawv, ua kom lub plawv dhia nrawm.
Dab tsi enzyme metabolizes digoxin?
Nws yog feem ntau metabolized los ntawm the CYP2C19 enzyme, ib tug tswv cuab ntawm pawg P450 sib xyaw ua haujlwm oxidase, txawm hais tias ib qho me me ntawm cov metabolism yog los ntawm CYP3A4, lwm P450 enzyme. Digoxin feem ntau metabolized sab nraum P450 system, tab sis txoj kev me me ntawm cov metabolism yog los ntawm CYP3A4.
CYP2C19 inhibitors yog dab tsi?
CYP2C19 catalyzes cov metabolism hauv ntau cov tshuaj, suav nrog cov tshuaj tiv thaiv proton twj tso kua mis (PPIs) (piv txwv li, omeprazole, lansoprazole, pantoprazole), antidepressants (piv txwv li, citalopram thiab amitriptyline), antiplatelet tshuaj (piv txwv li, clopidogrel), tshuaj tua kab mob (xws li, voriconazole), thiab tshuaj tiv thaiv kab mob (xws li, cyclophosphamide).
Pom zoo:
Qhov twg yog qhov mob thiab qhov twg yog qhov ceeb?
Panic (lub suab los ntawm Matt Frewer) yog lub ntsej muag ntsuab-xiav nrog lub cev ntev. Thaum nws yog me ntsis cunning dua Pain, nws paranoia txhais tau hais tias nws yog heev ceev faj thiab ntau cynical nyob rau hauv lub sij hawm, yog li nws tej zaum yuav ntse dua ib tug ntawm ob.
Thaum cawv yog metabolised?
Feem ntau cawv yog tawg, lossis metabolised, los ntawm ib qho enzyme hauv koj lub siab hlwb hu ua cawv dehydrogenase (ADH). ADH rhuav tshem cawv rau hauv acetaldehyde, thiab tom qab ntawd lwm enzyme, aldehyde dehydrogenase (ALDH), sai sai acetaldehyde rau hauv acetate .
Cov ntsia liaj qhov rooj nyob rau hauv qhov phem 3 nyob qhov twg?
Tus Neeg Siab Phem 3 tus ntsia liaj qhov rooj tau pom nyob rau hauv chav me me tsis muaj npe txuas nrog lub Chaw nres tsheb hauv plawv nroog . Kuv puas yuav tsum muab cov ntsia hlau txiav Resident Evil 3? Koj tsis tuaj yeem pov tseg cov khoom koj xav tau rau lub hom phiaj, xws li lub xauv xauv lossis ntsia liaj qhov rooj.
Dab tsi yog metabolised hauv siab?
Lub siab ua lub luag haujlwm tseem ceeb hauv txhua yam txheej txheem metabolic hauv lub cev. Hauv cov metabolism hauv rog, lub siab lub hlwb zom cov rog thiab tsim lub zog. Lawv kuj tsim txog 800 mus rau 1,000 ml ntawm cov kua tsib ib hnub. … Lub siab hlwb hloov ammonia mus rau ib yam khoom uas muaj tshuaj lom tsawg heev hu ua urea, uas tso rau hauv cov ntshav .
Paracetamol metabolised li cas?
Paracetamol yog metabolised ntau hauv daim siabthiab tawm hauv cov zis feem ntau yog glucuronide thiab sulfate conjugates. Tsawg dua 5% raug tshem tawm tsis hloov pauv. Cov metabolites ntawm paracetamol suav nrog me me hydroxylated intermediate uas muaj hepatotoxic kev ua haujlwm .
