Vim li cas triose phosphate isomerase catalytically zoo meej?

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Vim li cas triose phosphate isomerase catalytically zoo meej?
Vim li cas triose phosphate isomerase catalytically zoo meej?

Video: Vim li cas triose phosphate isomerase catalytically zoo meej?

Video: Vim li cas triose phosphate isomerase catalytically zoo meej?
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TRIOSEPHOSPHATE ISOMERASE (TIM, los yog TPI) TIM yog ib qho catalytically zoo meej enzyme nyob rau hauv lub siab hais tias nws kcat / Km tus nqi yog nyob rau hauv lub diffusion-limited ntau yam, thiab vim catalytic efficiency. Nws tsis tuaj yeem txhim kho los ntawm kev hloov pauv ntawm cov tshuaj muaj pes tsawg leeg ntawm cov kuab tshuaj, lossis los ntawm kev hloov pauv ntawm cov amino acid theem ntawm enzyme.

Koj tuaj yeem qhia tau li cas yog tias muaj enzyme catalytically zoo meej?

Lab Methods in Enzymology: Protein Part A

Yog kcat/Km - uas yog qhov pom tseeb thib ob- kev txiav txim tus nqi tas mus li rau cov tshuaj tiv thaiv enzyme-catalyzed - mus txog qhov kev txwv tsis pub dhau (~ 10 8–10 9 M- 1 s-1), enzyme tsis tuaj yeem ua rau cov tshuaj tiv thaiv ib qho zoo dua thiab tau hais tias tau mus txog 'catalytic perfection.

Kev ua haujlwm ntawm triose phosphate isomerase hauv glycolysis yog dab tsi?

Triosephosphate isomerase yog ib qho txiaj ntsig zoo hauv metabolic enzyme uas catalyzes kev sib hloov ntawm dihydroxyacetone phosphate (DHAP) thiab D-glyceraldehyde-3-phosphate (G3P) hauv glycolysis thiab gluconeogenesis.

Vim li cas cov enzymes zoo kawg nkaus catalysts?

Ntxim qab kawg, muaj ntau yam enzymes uas muaj cov cuab yeej no thiab lawv cov txiaj ntsig siab tshaj plaws yog kwv yees li qub. Cov enzymes no raug hu ua "zoo meej" vim lawv tau mus txog qhov muaj nqis tshaj plaws… Qhov nrawm dua cov tshuaj tiv thaiv hauv catalysis los ntawm ib qho enzyme, qhov nyuaj rau tswj.

Dab tsi yog qhov ua haujlwm ntawm triose phosphate isomerase hauv glycolysis Dab tsi yog enzyme commission tus lej rau cov enzyme no?

EC no. CAS nr. Triose-phosphate isomerase (TPI lossis TIM) yog ib qho enzyme (EC 5.3. 1.1) uas catalyzes qhov kev hloov pauv ntawm triose phosphate isomers dihydroxyacetone phosphate thiab D-glyceraldehyde 3-phosphate.

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