Glycogenesis tshwm sim thaum cov ntshav qabzib siab txaus kom tso cov piam thaj ntau dhau los khaws cia hauv daim siab thiab cov leeg nqaij. Glycogenesis yog txhawb los ntawm cov tshuaj insulin.
Yuav ua li cas hom glycogenolysis tshwm sim?
Kev tawg ntawm glycogen los tsim cov piam thaj hu ua glycogenolysis. Nws tshwm sim hauv cytosol ntawm lub xovtooj ntawm tes thiab pom tias yog qhov rov qab cov tshuaj tiv thaiv ntawm glycogenesis: piv txwv li glycogenolysis tshwm sim thaum yoo mov thiab / lossis nruab nrab ntawm cov zaub mov.
Glycogenesis nyob qhov twg tshaj plaws?
Glycogen synthesis los ntawm cov piam thaj tshwm sim hauv ntau cov ntaub so ntswg, tab sis nws tseem ceeb tshwj xeeb hauv daim siab thiab cov leegqhov nws qhov loj thiab qhov ua haujlwm tseem ceeb dua.
Puas glycogenesis tshwm sim hauv lub xeev yoo mov?
Nyob hauv lub xeev pub, cov piam thaj nkag mus rau hepatocytes ntawm GLUT2 thiab yog phosphorylated los ntawm glucokinase thiab siv los ua ke glycogen los ntawm glycogen synthase (4). Hauv lub xeev yoo mov, glycogen yog hydrolyzed los ntawmglycogen phosphorylase los tsim cov piam thaj (glycogenolysis) (Fig. 1).
Dab tsi yog qhov pib ntawm glycogenesis?
Glycogenesis pib hauv glucose uas yog phosphorylated los ua qabzib-6-phosphate los ntawm cov enzymes hexokinase hauv cov leeg thiab glucokinase hauv siab. Cov kauj ruam tom ntej ntawm cov txheej txheem yog raws li nram no: Glucose-6-phosphate (los ntawm phosphoglucomutase) -> Glucose-1- phosphate.
