Pellagra tau pom thawj zaug ntawm cov neeg ua liaj ua teb Spanish los ntawm Don Gaspar Casal hauv 1735 Tus kab mob tawv nqaij uas txaus ntshai, nws tau hu ua 'mal de la rosa' thiab feem ntau yuam kev rau mob ruas. Pellagra qee zaum hu ua kab mob ntawm plaub Ds - dermatitis, raws plab, dementia thiab tuag.
Pellagra pib li cas?
Pellagra yog vim kev noj haus uas tsis muaj niacin txaus thiab tryptophan Pellagra thib ob yog vim muaj peev xwm siv cov niacin hauv cov khoom noj tsis zoo. Qhov no tuaj yeem tshwm sim los ntawm kev haus dej cawv, raws plab mus ntev, carcinoid syndrome, kab mob Hartnup, thiab ntau cov tshuaj xws li isoniazid.
Leej twg kawm pellagra xyoo 1914?
In 1914, the U. S. Kev Pabcuam Pej Xeem Kev Noj Qab Haus Huv Dr. Joseph Goldberger (1874-1929) twb paub txog nws txoj kev vam meej hauv kev sib ntaus sib tua hauv Teb Chaws Asmeskas thaum nws raug nug kom tshawb xyuas pellagra.
Pellagra nrhiav tau thaum twg?
In 1937, tus kws tshawb fawb Conrad Elvehjem pom tias nicotinic acid, lossis niacin, tiv thaiv thiab kho pellagra hauv dev. Nws ua haujlwm zoo ib yam hauv tib neeg. Niacin yog ib qho ntawm cov vitamins B. Thaum xyoo 1930s, kev ua haujlwm zoo tau ua kom nkag siab txog txoj kev cov vitamins ua haujlwm hauv chemistry ntawm peb lub cev.
pellagra pom nyob qhov twg?
Pellagra muaj ntau nyob rau hauv cov neeg pluag hauv ntiaj teb no, xws li Africa thiab India, qhov twg pob kws (los yog pob kws) yog cov zaub mov tseem ceeb. Qhov no yog vim pob kws yog qhov tsis zoo ntawm tryptophan thiab niacin. Hauv Tebchaws Meskas, pellagra tau nthuav dav thaum xyoo 1900's nyob rau sab qab teb qhov twg pob kws tau ua lub luag haujlwm loj hauv kev noj haus.
