Persistent polyclonal B-cell lymphocytosis (PPBL) yog ib yam kab mob uas tsis tshua muaj benign nrog cov kab mob lymphocytosis ntawm polyclonal keeb kwm, thawj zaug piav nyob rau hauv 1982, uas tshwm sim ntau zaus nyob rau hauv nruab nrab-hnub nyoog poj niam haus luam yeeb. Cov no feem ntau yog lymphocytosis me me thiab feem ntau tsis muaj cov tsos mob lossis tsis pom cov tsos mob xws li qaug zog.
Puas yog B hlwb polyclonal?
Polyclonal B cell teb yog ib hom kab mob tiv thaiv kab mobnthuav tawm los ntawm kev hloov pauv lub cev tiv thaiv kab mob ntawm cov tsiaj. Nws ua kom ntseeg tau tias ib qho antigen tau lees paub thiab tawm tsam los ntawm nws qhov sib tshooj, hu ua epitopes, los ntawm ntau lub clones ntawm B cell.
Dab tsi yog polyclonal B cell pejxeem?
Persistent polyclonal B-cell lymphocytosis (PPBL) yog ib yam kab mob tsis tshua muaj, uas feem ntau cuam tshuam rau cov poj niam hnub nyoog nruab nrab thiab cuam tshuam nrog kev haus luam yeeb. Nws yog tus cwj pwm los ntawm kev nthuav dav tsis tu ncua ntawm CD27 + IgM + IgD + B hlwb, muaj cov circulating binucleated lymphocytes thiab nce qib IgM cov ntshav.
Dab tsi ua rau polyclonal ua kom B hlwb?
Hloov pauv, kev ua kom muaj polyclonal tuaj yeem tshwm sim los ntawm cov kab mob mus rauzam cov tswv tsev tshwj xeeb, tiv thaiv kab mob los ntawm kev ua kom B cell clones, uas tsim cov tshuaj tiv thaiv kab mob tsis muaj kab mob tshwj xeeb.
Puas yog lymphoma polyclonal?
Nyob rau hauv ib nrab peb cov neeg mob cov pejxeem ntawm Reed-Sternberg hlwb yog polyclonal; nyob rau hauv lwm ib nrab, monoclonal los yog mixed cell pejxeem tau pom. Kev sib raug zoo nrog rau theem kho mob qhia tau hais tias polyclonal Hodgkin tus kab mob tuaj yeem tshwm sim raws li cov qog ntshav qog ntshav thoob plaws.
