Methylecgonine yog ib qho tseem ceeb tropane alkaloid pom nyob rau hauv coca nplooj. Nws yog metabolite ntawm cocaine, thiab tej zaum yuav siv tau ua ntej rau nws. Nws kuj tshwm sim raws li me me alkaloid hauv cov hauv paus hniav ntawm ntau hom Datura xws li Datura stramonium thiab Datura innoxia.
Dab tsi yog benzoylecgonine thiab ecgonine methyl ester?
Benzoylecgonine (BE) thiab ecgonine methyl ester (EME) yuav tsum yog cov khoom lag luam loj hauv tib neeg cov ntshav BE yog tsim los ntawm cov tshuaj hydrolysis ntawm methyl ester pawg, thiab me me ntawm EME yog tsim enzymati-cally los ntawm hydrolysis ntawm benzoyl ester (2, 4).
Ib nrab lub neej ntawm ecgonine methyl ester yog dab tsi?
Ecgonine methyl ester muaj kev tshem tawm ib nrab ntawm 4.2 hr, piv nrog 5.1 hr rau benzoylecgonine. Cov txiaj ntsig no qhia tau tias ecgonine methyl ester tso nyiaj rau feem ntau ntawm cov khoom lag luam urinary metabolic uas tsis tau pom dua yav dhau los ntawm cocaine.
Yuav tshuaj twg yog benzoylecgonine?
Benzoylecgonine yog qhov sib xyaw ua ke rau nyob rau hauv cov tshuaj yeeb dawb feem ntau urinalysesNws yog cov carboxylic acid ntawm cov yeeb yaj kiab, nws cov methyl ester. Nws yog tsim nyob rau hauv daim siab los ntawm cov metabolism hauv cocaine los ntawm hydrolysis, catalysed los ntawm carboxylesterases, thiab tom qab ntawd tawm hauv cov zis.
Ecgonidine methyl ester yog dab tsi?
Ecgonidine methyl ester mesylate yog a metabolite ntawm Cocaine (COC) Nws yog cov khoom lag luam pyrolysis tsim thaum tawg yeeb dawb, ua rau cov tshuaj no yog biomarker tshwj xeeb rau kev siv. ntawm crack cocaine, as opposed to hmoov cocaine uas tsis tsim methylecgonidine ua metabolite.
