Trypsin yog ib qho serine protease ntawm lub plab zom mov uas tsim tawm hauv cov txiav ua haujlwm tsis ua haujlwm, trypsinogen. Tom qab ntawd nws tau tso rau hauv cov hnyuv me, qhov twg enterokinase proteolytic cleavage ua rau nws mus rau hauv trypsin. Cov txiaj ntsig ua haujlwm trypsin tuaj yeem ua kom muaj trypsinogens ntxiv los ntawm autocatalysis.
trypsin ua haujlwm li cas?
Trypsinogen yog qhib los ntawm enterokinase, uas cleaves ib qho amino-terminal activation peptide (TAP). Active trypsin ces cleaves thiab activates tag nrho lwm yam pancreatic proteases, ib tug phospholipase, thiab colipase, uas yog tsim nyog rau lub physiological kev txiav txim ntawm pancreatic triglyceride lipase.
Dab tsi ua rau trypsin hauv pancreas?
Ua kom muaj trypsinogen
Trypsinogen yog qhib los ntawm enteropeptidase (tseem hu ua enterokinase). Enteropeptidase yog tsim los ntawm mucosa ntawm duodenum thiab nws cleaves peptide daim ntawv cog lus ntawm trypsinogen tom qab residue 15, uas yog ib tug lysine.
Zymogen dab tsi ua trypsin qhib?
Yog li, cov zymogens yuav tsum tau hloov mus rau tib lub sijhawm. Kev tswj hwm kev tswj hwm tau ua tiav los ntawm kev ua ntawm trypsinua tus nquag ua haujlwm ntawm tag nrho cov pancreatic zymogens-trypsinogen, chymotrypsinogen, proelastase, procarboxypeptidase, thiab prolipase, lipid degrading enzyme.
trypsin ua qhov twg?
Trypsin yog ib qho enzyme uas pab peb zom cov protein. Nyob rau hauv cov hnyuv, trypsin zom cov proteins, txuas ntxiv cov txheej txheem ntawm kev zom zaub mov uas pib hauv plab. Nws kuj tseem tuaj yeem raug hu ua proteolytic enzyme, lossis proteinase. Trypsin yog tsim los ntawm pancreas nyob rau hauv ib tug inactive daim ntawv hu ua trypsinogen.
