3.2. Coiled coils yog tsim thaum ob lossis ntau dua α-helices nws tus kheej sib sau ua ke los ntawm kev sib txuas ua ke los tsim ib sab laug-tes supercoil (Fig. 3.1C). Txawm hais tias dimers, trimers, thiab tetramers yog cov qauv siv ntau tshaj plaws, cov coiled-coils loj dua txog li xya helices tam sim no tuaj yeem raug tsim los [8].
coiled-coils pom nyob qhov twg?
Coiled-coils muaj nyob hauv proteins thoob plaws peb lub nceeg vaj ntawm lub neej. Coiled-coil domains ntawm qee cov proteins yuav luag tsis sib xws hauv ntu thiab ntev, ntxeev siab rau cov qauv thiab kev ua haujlwm rau cov amino acids raws li tag nrho ntev ntawm coiled-coil.
coil-coils tuav ua ke li cas?
Ib coiled-coil lossis superhelix yog tsim los ntawm coiling ob, peb lossis plaub α-helices ua ke. Cov helical strands tau tuav ua ke los ntawm lub zog hydrophobic tsim ntawm cov saw hlau tsis muaj polar los ntawm cov peptide sib txawv.
Cov qauv coiled yog dab tsi?
Coiled coils yog α-helical cov qauv uas cov helices raug mob ib ncig ntawm ib leeg los tsim cov pob khoom superhelical. Lawv feem ntau muaj ob lossis peb lub helices nyob rau hauv parallel lossis antiparallel orientation, tab sis cov qauv nrog xya thiab ntau dua helices tau txiav txim siab.
Puas muaj qhov sib txawv ntawm Helix thiab kauj?
Helix yog cov qauv thib ob thiab coiled coil yog cov qauv supersecondary tab sis ob qho tib si yog qhov tshwm sim ntawm sib cuam tshuam rogntawm cov amino acid uas nyob ib sab nyob ib ncig ntawm daim ntawv cog lus peptide.
