Norepinephrine ua rau beta-1 adrenergic receptors , ua rau nce siab hauv plawv thiab lub plawv. Txawm li cas los xij, qhov siab ntawm lub plawv dhia tsuas yog ib ntus xwb, raws li baroreceptor baroreceptor Baroreceptors (los yog archaically, pressoreceptors) yog cov sensors nyob rau hauv carotid sinus (ntawm lub bifurcation ntawm sab nraud thiab sab hauv carotids) thiab nyob rau hauv lub aortic arch. Lawv hnov cov ntshav siab thiab xa cov ntaub ntawv mus rau lub hlwb, kom tswj tau cov ntshav siab. https://en.wikipedia.org › wiki › Baroreceptor
Baroreceptor - Wikipedia
teb rau qhov nce ntshav siab ntxiv nrog rau kev ua kom lub suab nrov nrov thaum kawg ua rau lub plawv dhia tsis tu ncua.
Dab tsi receptors ua norepinephrine ua rau?
Norepinephrine tuaj yeem mus txuas rau peb lub ntsiab receptors: alpha1 (alpha-1), alpha-2, thiab beta receptors. Cov receptors no cais raws li G-protein ua ke receptors nrog inhibitory lossis excitatory teebmeem thiab sib txawv affinities rau norepinephrine.
Yuav ua li cas yog lub tshuab ua haujlwm ntawm Levophed?
Mechanism Of Action
Norepinephrine yog a peripheral vasoconstrictor (alpha-adrenergic action) thiab inotropic stimulator ntawm lub plawv thiab dilator ntawm coronary arteries (beta-adrenergic action).
Puas norepinephrine khi beta 2 receptors?
Nco ntsoov tias norepinephrine hauv physiologically cuam tshuam kev sib koom ua ke muaj me ntsis affinity rau beta2 receptors . Yog li ntawd, nws yuav txhawb nqa tsuas yog alpha 1 receptors uas ua rau muaj kev nce hauv peripheral vascular resistance.
Yog Levophed Alpha lossis Beta?
Levophed ua haujlwm ua cov vasoconstrictor peripheral ( alpha-adrenergic ua) thiab ua inotropic stimulator ntawm lub plawv thiab dilator ntawm coronary arteries (beta-adrenergic action).
