Nonsecretory multiple myeloma (NSMM) yog qhov tsis tshua muaj qhov sib txawv ntawm MM thiab suav txog kwv yees li 1% txog 5% ntawm txhua kis. Nws txhais tau tias yog mob myeloma yam tsis muaj kev kuaj pom monoclonal immunoglobulin ntawm cov ntshav lossis zis electrophoresis. Qhov kev sib txawv no feem ntau ua rau muaj kev nyuaj rau tus kws kho mob.
Tus kab mob uas tsis yog secretory yog dab tsi?
Tsis-secretory myeloma yog classical txhais tau tias yog clonal pob txha pob txha plasma hlwb ≥10% los yog biopsy proven plasmacytoma, pov thawj ntawm qhov kawg ntawm lub cev puas tsuaj uas tuaj yeem raug ntaus nqi rau hauv cov ntshav ntshav. cell proliferative disorder, tshwj xeeb tshaj yog hypercalcemia, lub raum tsis ua hauj lwm, anemia, los yog pob txha lesions, thiab tsis muaj ntshav thiab …
Nonsecretory multiple myeloma yog dab tsi?
Nonsecretory multiple myeloma (NSMM) yog ib qho tsis tshua muaj qhov txawv ntawm daim ntawv classic ntawm ntau yam myeloma (MM) thiab suav rau 1% txog 5% ntawm txhua kis ntawm MM. Kev nthuav qhia kev kho mob thiab kev tshawb pom hluav taws xob ntawm NSMM thiab MM yog tib yam. Kev kuaj mob ntawm MM yuav tsum tau kuaj pom tus kab mob monoclonal gammopathy hauv cov ntshav los yog zis.
Ntau npaum li cas tsis yog secretory myeloma?
Non secretory myeloma
In kwv 3 tawm ntawm txhua 100 tus neeg uas muaj myeloma (3%), cov hlwb myeloma tsim cov tshuaj immunoglobulin tsawg lossis tsis muaj (tseem hu ua paraprotein.). Qhov no ua rau nws nyuaj rau kev kuaj mob. Cov kws kho mob siv cov kev kuaj mob pob txha thiab kev tshuaj ntsuam xyuas (xws li PET-CT) txhawm rau kuaj xyuas thiab saib xyuas cov kab mob uas tsis yog secretory myeloma.
Oligosecretory myeloma yog dab tsi?
Oligosecretory ntau tus myeloma feem ntau yog tus cwj pwm los ntawm cov protein ntau ntawm <1.0 g / dL, zis protein ntawm < 200 mg / 24 teev, thiab dawb lub teeb saw tseem ceeb ntawm < 100 mg /L (los yog 10 mg/dL).[15]
