Thaum muaj peev xwm ua tau tuaj txog hauv lub paj hlwb, lub membrane depolarizes thiab voltage-gated Ca2+ channels qhib. Qhov tshwm sim Ca2+ influx ua rau exocytosis ntawm synaptic vesicles, uas ua rau tso tawm cov neurotransmitter.
Yuav ua li cas ion ua rau exocytosis ntawm synaptic vesicles?
Kev nkag mus ntawm calcium ions rau hauv "" ua rau exocytosis ntawm synaptic vesicles.
Dab tsi ua rau cov hlwv mus rau exocytosis?
Nyob rau hauv exocytosis, membrane-bound secretory vesicles yog nqa mus rau lub cell membrane, qhov chaw uas lawv dock thiab fuse ntawm porosomes thiab lawv cov ntsiab lus (piv txwv li, dej-soluble molecules) yog secreted rau hauv extracellular ib puag ncig. Qhov kev tso tawm no tuaj yeem ua tau vim lub vesicle hloov pauv nrog cov plasma membrane
Dab tsi ua rau endocytosis ntawm synaptic vesicles?
Dab tsi ua rau synaptic vesicle endocytosis? Cov lus teb yooj yim tshaj plaws rau cov lus nug ntawm dab tsi ua rau synaptic vesicle endocytosis yuav yog lub vesicle membrane nws tus kheej Nws paub tias (clathrin-mediated) retrieval ntawm synaptic vesicle membrane tuaj yeem cuam tshuam ib ntus los ntawm kev ua haujlwm- induced calcium influx [40].
Yuav ua li cas txhawb cov hlwv synaptic tso tawm?
Cov calcium influx ua rau cov hlwv synaptic, uas pob neurotransmitters, khi rau presynaptic membrane thiab tso tawm acetylcholine rau hauv cov synaptic cleft los ntawm exocytosis.
