Acetylcholine tso tawm los ntawm cov hlwb endothelial ua kom muaj kev sib haum xeeb hauv kev nthuav dav. J Physiol.
Yuav ua li cas cov hlwb endothelial tswj vasodilation?
Kev ua kom ET-B1 receptors ntawm endothelium ua rau vasodilatation los ntawm inducing tso tawm NO thiab PGI 2 [73, 74]. Hauv ED, ET-B1 receptors ntawm cov hlwb endothelial yog downregulated, thaum ET-B2 receptors ntawm cov leeg nqaij pob txha yog upregulated, yog li txhim kho vasoconstriction [75, 76].
Cov tshuaj vasoconstrictor twg yog tsim los ntawm vascular endothelial hlwb?
Lub vascular endothelium plays lub luag haujlwm tseem ceeb hauv kev tswj hwm vasoconstriction los ntawm kev sib txuas thiab tso tawm cov tshuaj vasodilator xws li nitric oxide (NO) thiab prostaglandinsLub innermost txheej ntawm vascular arterial phab ntsa muaj ib tug monolayer ntawm endothelial hlwb thiab connective cov ntaub so ntswg.
endothelium mediated vasodilation yog dab tsi?
Cov tshuaj endothelium-dependent vasodilators pom meej ua los ntawm kev txhawb nqa kev tso tawm EDRF los ntawm cov hlwb endothelial, uas tig mus ua kom cov kua dej guanylate cyclase hauv vascular du leeg hlwb. … Ntawm qhov kev txaus siab tseem ceeb yog tus kheej ntawm kev ua haujlwm substrates rau cGMP-kinase hauv vascular du leeg.
Yuav ua li cas txhawb cov hlwb endothelial?
Endothelial cell proliferation nyob rau hauv 72-teev lub sij hawm yog pom los ntawm kev nce ntxiv ntawm cov platelets uas tsis ua haujlwm (●) lossis los ntawm thrombin-activated (0.5 U / mL) platelets (▵).
