Thiazole is a π-electron-excessive heterocycle. … Hauv qhov sib piv, kev hloov pauv ntawm electrophilic ntawm thiazoles nyiam qhov chaw ntawm electron-nplua nuj C (5) txoj hauj lwm.
thiazole yog dab tsi?
Kev lag luam tseem ceeb thiazoles suav nrog cov tshuaj pleev xim ntau thiab cov tshuaj tua kab mob. Thifluzamide, Tricyclazole, thiab Thiabendazole tau ua lag luam rau kev tswj ntau yam kab tsuag ua liaj ua teb. Lwm qhov dav siv thiazole derivative yog cov tshuaj uas tsis yog-steroidal anti-inflammatory Meloxicam.
Tus qauv ntawm thiazole yog dab tsi?
Thiazole yog tsib-tus tswvcuab, tsis txaus ntseeg, cov phiaj xwm, π-hloov heteroaromatic uas muaj ib tus sulfur atom thiab ib qho pyridine-hom nitrogen atom ntawm txoj haujlwm 3 ntawm lub voj voog voj voog. Nws tseem hu ua 1, 3-thiazole.
Yuav tshuaj twg muaj thiazole nucleus?
Thiazole, heterocyclic nucleus yog tam sim no nyob rau hauv ntau lub zog pharmacologically active molecules xws li Sulfathiazole (cov tshuaj tua kab mob), Ritonavir (cov tshuaj tiv thaiv kab mob), Tiazofurin (antineoplastic tshuaj) thiab Abafungin (antifungal). tshuaj) etc.
Lub ntsiab lus twg muaj nyob hauv heteroatom hauv thiazole?
Thiazole, ib chav kawm ntawm cov organic tebchaw ntawm heterocyclic series cim los ntawm lub nplhaib qauv tsim los ntawm peb carbon atoms, ib nitrogen atom, thiab ib tug sulfur atom.
