FDA Ceeb Toom: Kev pheej hmoo tuag ntau ntxiv Lub thawv dub ceeb toom ceeb toom cov kws kho mob thiab cov neeg mob txog cov tshuaj uas yuav ua rau muaj kev phom sij. Quinidine tuaj yeem ua rau koj txoj kev pheej hmoo tuag. Koj qhov kev pheej hmoo yuav siab dua yog tias koj muaj kab mob hauv lub plawv.
quinidine ua rau arrhythmia li cas?
Mechanism of action
Zoo li tag nrho lwm cov chav kawm kuv cov tshuaj tiv thaiv kev mob arrhythmic, quinidine feem ntau ua haujlwm los ntawm kev thaiv lub nrawm sab hauv sodium tam sim no (INa). Quinidine's effect on INa is known as a ' siv dependent block'. Qhov no txhais tau hais tias ntawm lub plawv dhia siab dua, qhov thaiv nce, thaum lub plawv dhia qis, qhov thaiv txo qis.
Dab tsi yog qhov qhia rau quinidine?
Kev kho mob ntev nrog Quinidex (quinidine) yog qhia rau qee tus neeg mob uas muaj kev pheej hmoo siab ntawm cov tsos mob atrial fibrillation / flutter; Feem ntau cov neeg mob uas tau muaj yav dhau los ntu ntawm atrial fibrillation / flutter uas nquag heev thiab tsis zoo rau kev ua siab ntev, nyob rau hauv kev txiav txim ntawm tus kws kho mob thiab tus neeg mob, …
quinidine toxicity yog dab tsi?
Quinidine cov kev mob tshwm sim muaj ntau yam los ntawm kev tsis txaus ntseeg ntawm lub paj hlwb thiab plab hnyuv siab rau myocardial toxicity. Cov tsos mob tshwm sim ntau tshaj plaws yog raws plab, xeev siab, thiab ntuavQhov kev pheej hmoo ntawm toxicity yog ntau dua thaum cov ntshav plasma quinidine ntau dua 4 mg / L.
quinidine ua li cas rau lub siab?
Quinidine yog siv kho qee yam ntawm lub plawv dhia tsis tu ncua. Quinidine yog nyob rau hauv ib chav kawm ntawm cov tshuaj hu ua antiarrhythmic tshuaj. Nws ua haujlwm los ntawm kev ua kom koj lub siab tiv taus ntau yam kev ua haujlwm txawv txav.
