Chaperonins yog tus cwj pwm los ntawm cov qauv sib dhos ob lub nplhaib thiab pom nyob rau hauv prokaryotes, hauv cytosol ntawm eukaryotes, thiab hauv mitochondria Lwm hom chaperones koom nrog hauv kev thauj mus los ntawm daim nyias nyias., piv txwv li daim nyias nyias ntawm mitochondria thiab endoplasmic reticulum (ER) hauv eukaryotes.
Molecular chaperones khi nyob qhov twg?
Molecular chaperones cuam tshuam nrog nthuav tawm lossis ib nrab folded protein subunits, piv txwv li. Nascent chains tshwm sim los ntawm ribosome, los yog txuas ntxiv chains tau translocated hla subcellular membranes.
Dab tsi yog molecular chaperones piv txwv?
Piv txwv ntawm chaperon proteins yog "heat shock proteins" (Hsps).… Ob qho piv txwv ntawm Hsps yog Hsp70 thiab Hsp60 Hsp70. Hsp70 chaperone proteins yog folding catalysts uas pab nyob rau hauv ntau yam folding txheej txheem xws li refolding los yog misfolding ntawm aggregated proteins, thiab folding thiab assembling ntawm tshiab proteins.
Puas txhua lub hlwb puas muaj chaperone proteins?
Ib yam li ntawd, tsis yog txhua tus molecular chaperone yog cov protein uas muaj kev ntxhov siab. Raws li tej zaum yuav inferred los ntawm lawv multiplicity ntawm kev ua, molecular chaperones promiscuous; Lawv cuam tshuam nrog ntau yam molecules. Lawv kuj yog ubiquitous; lawv tshwm sim hauv txhua lub hlwb, cov ntaub so ntswg, thiab cov kabmob, nrog rau qhov paub tsawg heev.
Dab tsi yog chaperon molecules thiab vim li cas lawv tseem ceeb rau cov hlwb?
Molecular chaperones yog qhov kev daws teeb meem rau cov teeb meem no. Lawv pab lwm cov proteins kom tau txais thiab tswj lawv cov qauv, txhawb cov txheej txheem ntawm tes, thiab tseem txuas cov haujlwm ntawm cov proteins rau cov xwm txheej ntxhov siab ntawm tes.
