Nyob rau hauv neurons, lub cell nkag mus rau hauv lub xeev ntawm hyperpolarization tam sim ntawd tom qab lub cim ntawm ib tug muaj peev xwm ua. Thaum hyperpolarized, cov neuron nyob rau hauv lub sijhawm refractory uas kav ntev kwv yees 2 milliseconds, lub sijhawm uas cov neuron tsis tuaj yeem tsim cov peev txheej tom ntej.
Yuav ua li cas thaum lub sijhawm hyperpolarization?
Hyperpolarization yog ib theem uas qee cov poov tshuaj nyob twj ywm qhib thiab sodium channels rov pib duaIb lub sijhawm ntawm cov poov tshuaj permeability nce ntxiv ua rau cov poov tshuaj ntau dhau ua ntej cov kab poov tshuaj kaw. Qhov no ua rau hyperpolarization raws li pom hauv me ntsis poob tom qab qhov nce.
Cov channel twg qhib thaum lub sijhawm hyperpolarization?
On hyperpolarization, HCN channels qhib thiab nqa ib Na+ sab hauv tam sim no uas tig mus depolarizes ntawm tes. Lawv yog modulated los ntawm cyclic nucleotides, thiab yog li, ob peb tus neeg xa xov liaison thib ob qhia rau hluav taws xob ua haujlwm (4). HCN channels, tseem hu ua pacemaker channels, ua haujlwm ntau yam.
Lub rooj vag twg qhib thaum lub sijhawm hyperpolarization?
In the hyperpolarization stage, the K+ rooj vag kaw thiab Na+ rooj vag nyob twj ywm kaw. Raws li cov kev cuam tshuam uas tswj cov peev txheej sib npaug (Na+/K+ twj tso kua mis thiab K to channel), cov cell membrane rov qab mus rau nws so. xeev.
Yuav ua li cas thaum lub sij hawm depolarization ntawm paj hlwb impulse kis?
Thaum muaj peev xwm ua tau mus txog axon davhlau ya nyob twg, nws depolarizes daim nyias nyias thiab qhib qhov hluav taws xob-gated Na+ channels Na + ions nkag mus rau hauv lub cell, ntxiv depolarizing lub presynaptic membrane. Qhov no depolarization ua rau voltage-gated Ca2+ channel qhib.
