Introns yog cov ntawv tsis yog ntawm RNA cov ntawv sau, lossis DNA encoding nws, uas tau sib cais tawm ua ntej RNA molecule raug txhais ua cov protein. Cov seem ntawm DNA (los yog RNA) uas code rau cov proteins hu ua exons.
Introns spliced tawm qhov twg?
Thaum tus txheej txheem ntawm splicing, introns raug tshem tawm los ntawm pre-mRNA los ntawm spliceosome thiab exons yog spliced rov qab ua ke. Yog tias cov introns tsis raug tshem tawm, RNA yuav raug muab txhais ua cov protein tsis ua haujlwm. Splicing tshwm sim nyob rau hauv lub nucleus ua ntej RNA migrate mus rau lub cytoplasm.
Thaum twg thiab qhov twg raug tshem tawm?
Introns raug tshem tawm los ntawm cov ntawv sau thawj zaug los ntawm kev sib cais ntawm kev khaws cia ua ntu zus hu ua splice sites. Cov chaw no muaj nyob ntawm 5′ thiab 3′ kawg ntawm introns Feem ntau, RNA ib ntus uas raug tshem tawm pib nrog dinucleotide GU ntawm nws 5′ kawg, thiab xaus nrog AG ntawm nws. 3′ kawg.
Dab tsi ua rau introns tsim lub voj?
R-loops, Introns thiab DNA puas
Introns yog cov cheeb tsam tsis-coding nyob rau hauv cov noob uas tau sau nrog rau cov cheeb tsam coding ntawm cov noob, tab sis tom qab ntawd raug tshem tawm ntawm thawj RNA cov ntawv sau los ntawm splicing Ua haujlwm ntawm thaj chaw ntawm DNA feem ntau tsim R-loops uas yooj yim rau DNA puas.
Dab tsi yog splicing yog vim li cas nws yuav tsum tau?
Nws yog qhov tsim nyog hauv eukaryotic hlwb vim eukaryotic noob muaj cov cheeb tsam uas tsis yog coding (hu ua introns) nyob nruab nrab ntawm cheeb tsam coding (paub tias exons). Yog li txhawm rau ua kom muaj cov protein ua haujlwm los ntawm mRNA, cov introns yuav tsum raug tshem tawm thiab qhov no yog ua los ntawm kev sib txuas.
