Thaum lub endosome tau matured mus rau hauv lub endosome/MVB lig thiab fuses nrog ib tug lysosome, lub vesicles nyob rau hauv lub lumen raug xa mus rau lub lysosome lumen. Proteins tau cim rau txoj hauv kev no los ntawm kev sib ntxiv ntawm ubiquitin.
YPob endosomes hloov mus ua lysosomes?
Kev thauj los ntawm lig endosomes mus rau lysosomes yog, hauv qhov tseem ceeb, unidirectional, txij li qhov kawg endosome yog "siv" nyob rau hauv tus txheej txheem ntawm fusing nrog lysosome. Yog li ntawd, soluble molecules nyob rau hauv lub lumen ntawm endosomes yuav zoo li mus rau hauv lysosomes, tshwj tsis yog tias lawv tau txais nyob rau hauv qee txoj kev.
Puas endosome thiab lysosome tib yam?
Qhov sib txawv tseem ceeb ntawm endosome thiab lysosome yog qhov endosome yog vacuoleuas nyob ib puag ncig cov ntaub ntawv hauv lub sijhawm endocytosis, qhov lysosome yog vacuole uas muaj hydrolytic enzymes.… Endosome thiab lysosome yog ob hom membrane-bound vesicles hauv cell.
Ua late endosomes fuse nrog lysosomes?
Late endosomes uas muaj cov lumenal vesicles fusenrog lysosomes. … Cov endosomes lig muaj ntau lub lumenal vesicles dua li thaum ntxov endosomes thiab feem ntau piav raws li lub cev multivesicular (MVBs).
Yuav ua li cas hauv qhov endosome?
Endosomes feem ntau yog intracellular sorting organelles. Lawv tswj kev lag luam ntawm cov protein thiab lipidsntawm lwm cov subcellular compartments ntawm secretory thiab endocytic txoj kev, tshwj xeeb tshaj yog cov plasma membrane Golgi, trans-Golgi network (TGN), thiab vacuoles / lysosomes.