Dopa decarboxylase nyob rau hauv ntau qhov chaw ntawm lub hlwb thiab feem ntau pom hauv basal ganglia. Dopa decarboxylase catalyzes decarboxylation ntawm L-3, 4-dihydroxyphenylalanine (DOPA) rau dopa, L-5-hydroxytryptophan rau serotonin thiab L-tryptophan rau tryptamine.
Dopa decarboxylase yog dab tsi?
DOPA decarboxylase (DDC) yog lub luag haujlwm rau kev sib txuas ntawm cov neurotransmitters tseem ceeb dopamine thiab serotonin ntawm decarboxylation ntawmL-3, 4-dihydroxyphenylalanine (L-DOPA) thiab L- 5-hydroxytryptophan, feem. DDC tau cuam tshuam rau ntau qhov chaw kho mob, suav nrog Parkinson tus kab mob thiab kub siab.
Dopaminergic decarboxylation yog dab tsi?
DOPA decarboxylase (DDC) yog lub luag haujlwm rau kev hloov pauv ntawm cov tshuaj tsw qab amino acids rau hauv lawv cov amines sib raug thaum lub sijhawm sib txuas ntawm ntau cov neurotransmitters tseem ceeb. … AADCD yog ib qho yuam kev hauv yug los hauv neurotransmitter metabolism uas ua rau ua ke serotonin thiab catecholamine deficiency.
AADC nyob qhov twg?
AADC tau pom nyob rau hauv ntau yam kabmob xws li raum, siab, ntsws, hlab ntsha, hlwb, thiab qaum qaumhauv ntau hom tsiaj thiab tib neeg (Holtz li al.., 1938; Hökfelt et al., 1973; Hardebo et al., 1979; Jaeger et al., 1983, 1984; Zhu and Juorio, 1995; Kubovcakova et al., 2004; Kitahama, 20et al.
Lub luag haujlwm ntawm dopa decarboxylase yog dab tsi?
Lub enzyme DOPA decarboxylase (aromatic-L-amino-acid decarboxylase, DDC) ua lub luag haujlwm lub luag haujlwm tseem ceeb hauv dopaminergic system thiab koom nrog kev nce thiab decarboxylation ntawm amine precursors hauv cov ntaub so ntswg peripheralSib nrug los ntawm catecholamines, DDC catalyses lub biosynthesis ntawm serotonin thiab kab amines.
