Cov ntaub so ntswg epithelial tuav tsis tu ncua los ntawm kev tsim cov hlwv nruj ntawm cov hlwb. Cov chav ua haujlwm yooj yim uas tsim cov nplaum sib tiv tauj thoob plaws lub hlwb yog cov hlua khi nruj, uas yog tsim los ntawm cov proteins transmembrane xws li claudin, occludin thiab tricellulin.
Yuav ua li cas cov kev sib tshuam nruj?
Tight Junctions feem ntau tsim los ntawm kev sib cuam tshuam ntawm cov tswv cuab ntawm Claudin tsev neeg ntawm cov proteins thiab lwm yam kev hloov pauv hauv cov khoom xws li occludin, tricellulin thiab junctional adhesion molecules (JAMs).
Cov kev sib tshuam nruj rau dab tsi?
Tight junctions tsim ciam teb ntawm apical thiab basolateral cell nto nyob rau hauv polarized epithelia, thiab txhawb nqa kev saib xyuas ntawm tes polarity los ntawm kev txwv kev sib xyaw ntawm apical thiab basolateral transmembrane Cheebtsam.
Cov kev sib tshuam ua li cas?
Txoj kev sib tshuam-tsim rau homojunction. Kev sib koom ua ke cais n-hom thiab p-hom semiconductors tshwm sim hauv ib qho khoom tab sis nrog tsis sib xws hauv cov hluav taws xob thiab qhovntom. Qhov no tau them nyiaj kom txog rau thaum qhov kev tawm tsam hauv qhov hluav taws xob nres nres cov neeg nqa khoom tsiv teb tsaws.
Cov molecules dab tsi tuaj yeem dhau los ntawm kev sib tshuam nruj?
Cov no suav nrog ntau cov proteins transmembrane xws li claudins, junctional adhesion molecules (JAMs), coxsackie adenovirus receptor (CAR), thiab cov tswv cuab ntawm cov kev sib tshuam nruj txuam nrog marvel protein. (TAMP) tsev neeg, suav nrog marvelD3, occludin, thiab tricellulin.
