Cov txheej txheem:
- Yuav ua li cas cov adjuvants txhim kho lub cev tiv thaiv kab mob?
- Yuav ua li cas adjuvants txhim kho lub immunogenicity ntawm antigens?
- Pob adjuvants txhawb lub cev tiv thaiv kab mob rau cov tshuaj tiv thaiv nyob?
- Yuav ua li cas yog cov tshuaj tiv thaiv kab mob?
Video: Adjuvants hauv tshuaj tiv thaiv ua haujlwm li cas?
2024 Tus sau: Fiona Howard | [email protected]. Kawg hloov kho: 2024-01-10 06:38
Ib qho tshuaj tiv thaiv yog ib yam khoom uas txhim kho lub cev tiv thaiv kab mob cov lus teb rau qhov muaj cov tshuaj tiv thaivLawv feem ntau siv los txhim kho kev siv tshuaj tiv thaiv. Feem ntau, lawv tau txhaj nrog ib qho antigen los pab lub cev tiv thaiv kab mob tsim cov tshuaj tiv thaiv kab mob uas tawm tsam cov tshuaj tiv thaiv.
Yuav ua li cas cov adjuvants txhim kho lub cev tiv thaiv kab mob?
Muaj pov thawj qhia tias cov neeg ua haujlwm kho mob siv ib lossis ntau lub tswv yim hauv qab no txhawm rau txhawm rau tiv thaiv lub cev tiv thaiv kab mob: (1) tso tawm cov tshuaj tiv thaiv nyob rau ntawm qhov chaw txhaj tshuaj (depot effect), (2) kev tswj hwm ntawm cytokines thiab chemokines, (3) cellular recruitment at the site of txhaj, (4) nce antigen uptake …
Yuav ua li cas adjuvants txhim kho lub immunogenicity ntawm antigens?
Adjuvant yog ib qho kev npaj uas txhim kho kev tiv thaiv kab mob antigen. Adjuvant yog siv nyob rau hauv zus tau tej cov polyclonal thiab monoclonal antibodies. Lub adjuvant tso cai rau lub sijhawm ntev thiab qeeb tso tawm ntawm antigen hauv lub cev. Adjuvant tseem tiv thaiv cov tshuaj tiv thaiv los ntawm qhov tsis muaj qhov tshwj xeeb stimulation ntawm lub cev tiv thaiv kab mob.
Pob adjuvants txhawb lub cev tiv thaiv kab mob rau cov tshuaj tiv thaiv nyob?
Txawm hais tias nws tau tsim muaj tseeb tias adjuvants tuaj yeem txhim kho cov tshuaj tiv thaiv kab mob rau kev txhaj tshuaj rau tib neeg, txog niaj hnub no tsis muaj cov tshuaj tiv thaiv tau pom tias ua rau muaj qhov loj ntawm cov tshuaj antigen tshwj xeeb CD8 + T cell teb txhawb los ntawm cov tshuaj tiv thaiv kab mob muaj sia xws li YF-17D (ref.109).
Yuav ua li cas yog cov tshuaj tiv thaiv kab mob?
Ib qho tshuaj tiv thaiv yog ib qho khoom siv hauv qee cov tshuaj tiv thaiv uas pab tsim kom muaj lub cev tiv thaiv kab mob zoo dua rau cov neeg tau txais cov tshuaj tiv thaiv. Hauv lwm lo lus, adjuvants pab cov tshuaj tiv thaiv ua haujlwm zoo dua.
Pom zoo:
Dab tsi yog qhov txawv ntawm cov tshuaj tiv thaiv thiab tshuaj tiv thaiv?
Raws li nouns qhov txawv ntawm antitype thiab hom yog hais tias antitype yog ib yam dab tsi uas yog cim los yog sawv cev los ntawm ib homthaum hom yog ib pab pawg raws li cov yam ntxwv sib koom; ib hoob . Antitype txhais li cas? 1a:
Tshuaj tiv thaiv tiv thaiv kab mob li cas?
Cov no yog cov enzymes uas rhuav tshem cov kab mob los ntawm kev rhuav tshem lawv cov phab ntsa ntawm tes. Lysozymes muaj nyob rau hauv qaub ncaug, kua mis thiab hnoos qeev, nrog rau cov kua muag. Lysozymes yog cov tshuaj yog li, zoo li lub plab acid, lawv yog ib hom tshuaj tiv thaiv kab mob .
Cov tshuaj tiv thaiv puas tiv thaiv kab mob?
Cov ntaub ntawv tshiab kawg qhia tau tias kev txhaj tshuaj tsis yog tiv thaiv tib neeg cov tshuaj tiv thaiv xwb, nws txo qis txoj hauv kev uas lawv tuaj yeem kis tus kabmob mus rau lwm tus. Cov tshuaj tiv thaiv COVID-19 puas tiv thaiv kev sib kis?
Puas yog cov tshuaj tiv thaiv kab mob sib txuas tau suav tias yog kev tiv thaiv kab mob?
Antibody drug conjugates (ADCs) yog ib hom tshuaj tiv thaiv kab mob. Lawv yog tsim los ntawm peb yam: monoclonal antibody (mAb) thiab cytotoxic payload ua los ntawm cov kws khomob kws khomob, uas txuas nrog ua ke siv cov tshuaj sib txuas . Puas yog tshuaj tiv thaiv kab mob tib yam li kev tiv thaiv kab mob?
Cov tshuaj tiv thaiv puas muaj txiaj ntsig tiv thaiv delta variant?
Cov tshuaj tiv thaiv Delta muaj txiaj ntsig zoo li cas ntawm cov tshuaj tiv thaiv COVID-19? Hais txog Delta Variant: Cov tshuaj tiv thaiv muaj txiaj ntsig zoo rau kev mob hnyav, tab sis Delta variant ua rau ntau dua Kev kis kab mob thiab kis tau sai dua li cov qauv ua ntej ntawm tus kab mob uas ua rau COVID-19.
