Cov tshuaj lom neeg: Vinca muaj indole alkaloids ntau, feem ntau yog vincristine thiab vinblastine. Vinca kuj muaj lwm cov alkaloids xws li ajmalicine, serpentine thiab lochnerine ua cov tshuaj lom neeg.
Dab tsi ntawm vinca yog tshuaj?
Vinca alkaloids yog ib pawg ntawm cov tshuaj tau los ntawm Madagascar periwinkle cog. Lawv tau muab rho tawm los ntawm cov paj liab periwinkle, Catharanthus roseus G. Don thiab muaj cov nyhuv hypoglycemic nrog rau cov teebmeem cytotoxic.
Koj rho tawm vinca alkaloids li cas?
Cov alkaloids (120 gm) yog yaj hauv 400 ml ntawm chloroform thiab muab rho tawm nrog pH 3 phosphate tsis (ib litre). Cov txheej chloroform yog qhuav dhau los ntawm cov dej tsis muaj dej Na2SO4, lim thiab concentrated hauv lub tshuab nqus tsev kom them taus 60 grams ntawm alkaloidal sib tov. Qhov no yog yaj hauv 240 ml ntawm chloroform.
Hom alkaloids muaj nyob hauv vinca dab tsi?
Vinca alkaloids yog qhov paub zoo ntawm cov tshuaj tau los ntawm Madagascar periwinkle (Catharanthus roseus). Plaub qhov loj vinca alkaloids siv nyob rau hauv ntau yam kev kho mob qog noj ntshav yog vinblastine, vincristine (los yog semisynthetic derivatives), vindesine, thiab vinorelbine(Fig. S1A).
Puas yog vincristine tseem siv?
“Tam sim no tau siv ntau ntawm peb kho mob qog noj ntshav rau menyuam yaus, los ntawm peb hom mob qog noj ntshav feem ntau, mob qog ntshav qog ntshav qog ntshav, mus rau lymphomas, suav nrog Hodgkin thiab non-Hodgkin lymphoma.,”nws hais. Nws kuj tau siv rau ntau cov qog nqaij hlav, nrog rau cov qog hlwb, Wilms qog thiab neuroblastoma.
