Rifaximin yog cov tshuaj tua kab mob tsis zoo uas tau xav tias yuav txo qis ammonia los ntawm kev tshem tawm cov kab mob ammonia-ua rau cov kab mob hauv plab. Ntau qhov kev tshawb fawb me me tau qhia tias rifaximin yog zoo hauv kev kho mob hnyavHE thiab ua tau zoo heev.
Lactulose kho kab mob siab encephalopathy li cas?
Cov tshuaj no yog siv los ntawm qhov ncauj lossis lub qhov quav los kho lossis tiv thaiv kab mob siab (hepatic encephalopathy). Nws tsis kho qhov teeb meem, tab sis yuav pab txhim kho kev puas siab puas ntsws. Lactulose yog ib qho colonic acidifier uas ua haujlwm los ntawm kev txo cov ammonia hauv cov ntshav
hom kev ua ntawm rifaximin yog dab tsi?
Mechanism of Action
Rifaximin yog ib qho tsis zoo absorbed bactericidal rifamycin derivative, uas inhibits kab mob protein synthesis los ntawm irreversibly khi rau RpoB, beta-subunit ntawm cov kab mob. DNA-nyob RNA polymerase (3).
Vim li cas rifaximin muab rau cirrhosis?
Rifaximin txo qis ascites thiab txhim kho kev muaj sia nyob ntawm cov neeg mob cirrhotic nrog refractory ascites. Ib qho kev ua tau zoo yog tias rifaximin tswj cov qauv thiab kev ua haujlwm ntawm cov kab mob hauv plab, yog li txhim kho cov kab mob hauv lub cev.
Vim li cas thiaj muab tshuaj tua kab mob rau tus kab mob siab hepatic encephalopathy?
Ntau cov tshuaj tua kab mob hauv qhov ncauj, suav nrog neomycin, metronidazole, thiab rifaximin, yog zoo txo qis cov ntshav ammoniathiab tseem siv rau hauv kev tswj cov kab mob hepatic encephalopathy (Alexander 1992; Zeneroli 2005).