Nyob rau hauv pernicious anemia antibodies los ntawm?

2024 Tus sau: Fiona Howard | [email protected]. Kawg hloov kho: 2023-12-16 01:49

Pernicious anemia yog tshwm sim los ntawm vitamin B12 deficiency vim tsis muaj qhov tseem ceeb hauv lub cev. Qhov xwm txheej no tshwm sim feem ntau thaum lub cev tiv thaiv kab mob tsom nws cov ntaub so ntswg thiab tsim cov tshuaj tiv thaiv kab mob tawm tsam parietal hlwb thiab / lossis qhov tseem ceeb.

Yuav ua li cas cov tshuaj tiv thaiv muaj nyob rau hauv pernicious anemia?

Muaj ob hom autoantibodies txheeb xyuas nyob rau hauv pernicious anemia: intrinsic factor antibodies (IFA) thiab parietal cell antibodies (PCA). Parietal cell antibodies ua lawv cov haujlwm tawm tsam parietal cell proton twj ATPase.

Y Yuav ua li cas thiaj tiv thaiv pernicious anemia?

Pernicious anemia yog hom vitamin B12 anemia. Lub cev xav tau cov vitamin B12 los ua cov qe ntshav liab. Koj tau txais cov vitamin no los ntawm kev noj zaub mov xws li nqaij, nqaij qaib, shellfish, qe, thiab khoom noj siv mis.

txhais li cas kom muaj qhov muaj txiaj ntsig zoo hauv cov tshuaj tiv thaiv kab mob?

Ib qho txiaj ntsig IFAB qhov ntsuas tau pom tau tias qhov muaj cov tshuaj autoantibodies mus rau qhov tseem ceeb. Kev sib xyaw ntawm megaloblastic anemia, ntshav vitamin B12 tsawg, thiab muaj cov ntshav IFAB txhawb kev kuaj mob ntawm pernicious anemia.

qhov tseem ceeb ntawm qhov tseeb tuaj qhov twg?

Intrinsic yam yog cov protein uas pab koj cov hnyuv nqus cov vitamin B12. Nws yog tsim los ntawm cells hauv plab kab.

20 cov lus nug ntsig txog pom

Dab tsi rhuav tshem qhov tseeb?

In pernicious anemia, lub cev ua cov tshuaj tiv thaiv kab mob uas tawm tsam thiab rhuav tshem cov parietal (pa-RI-eh-tal) hlwb. Cov hlwb no kab lub plab thiab ua rau qhov tseem ceeb. Vim li cas qhov no autoimmune teb tshwm sim tsis paub. Raws li qhov tshwm sim ntawm qhov kev tawm tsam no, lub plab nres ua qhov tseem ceeb.

Yuav ua li cas paub yog tias koj tsis muaj qhov tseem ceeb?

Feem ntau tshwm sim los ntawm qhov tsis muaj cov protein hauv plab uas paub tias yog qhov tseem ceeb, tsis muaj vitamin B12 tsis tuaj yeem nqus tau. Cov tsos mob ntawm pernicious anemia yuav muaj xws li qaug zog, qaug zog, mob plab, lub plawv dhia tsis zoo (tachycardia), thiab / lossis mob hauv siab.

Dab tsi ua rau cov tshuaj tiv thaiv kab mob hauv lub cev?

Intrinsic factor antibodies yog cov proteins uas tsim los ntawm lub cev tiv thaiv kab mob uas cuam tshuam nrog pernicious anemiaQhov kev kuaj no kuaj pom cov tshuaj tiv thaiv kab mob hauv lub cev (IF antibody) ncig hauv cov ntshav. Intrinsic yam yog cov protein uas tsim los ntawm ib hom ntawm cov hlwb tshwj xeeb uas kab lub plab phab ntsa hu ua parietal cells.

Leej twg txaus ntshai tshaj plaws rau pernicious anemia?

Risk Factors

Pernicious anemia muaj ntau dua hauv cov neeg ntawm Northern Europe thiab African qhovntsej thiaj tsis mobdua li lwm haiv neeg. Cov neeg laus kuj muaj kev pheej hmoo siab dua rau tus mob. Qhov no feem ntau yog vim tsis muaj lub plab acid thiab qhov tseem ceeb hauv lub cev, uas tiv thaiv txoj hnyuv me los ntawm kev nqus cov vitamin B12.

Yuav ua li cas yog tias koj tsis muaj qhov tseem ceeb?

Qhov tseem ceeb ntawm lub cev yog ib yam khoom uas muaj nyob hauv plab. Koj xav tau cov tshuaj no kom nqus tau cov vitamin B12 los ntawm cov khoom noj. Qhov tsis muaj qhov tseem ceeb hauv lub cev ua rau pernicious anemia thiab vitamin B12 deficiency, uas tuaj yeem ua rau mob ntshav qab zib thiab lub hlwb thiab lub paj hlwb (neurological) teeb meem.

Puas pernicious anemia hloov mus ua leukemia?

Cov tib neeg uas muaj ntshav qab zib ntau kuj tseem muaj kev pheej hmoo ntau ntxiv ntawm kev tsim myeloma (los yog: 1.55), mob ntshav qab zib myeloid (OR: 1.68) thiab myelodysplastic syndromes (los yog: 2.87).

Puas pernicious anemia ua rau koj lub neej luv?

Tam sim no, kev paub ntxov ntxov thiab kev kho mob ntawm tus kab mob pernicious anemia muab qhov qub, thiab feem ntau tsis yooj yim, lifespanKev kho mob qeeb tso cai rau kev mob ntshav qab zib thiab cov teeb meem neurologic. Yog tias cov neeg mob tsis kho tus kab mob thaum ntxov, cov teeb meem ntawm lub paj hlwb tuaj yeem ua mus tas li.

Koj puas tuaj yeem haus cawv yog tias koj muaj ntshav qab zib txaus?

suav nrog cov khoom noj uas muaj vitamin B12 ntau, xws li qe, mis nyuj, thiab nqaij. Tsis txhob haus cawv thaum koj raug kho. Cawv tuaj yeem tiv thaiv lub cev los ntawm kev nqus cov vitamin B12. Noj cov zaub mov uas muaj folate (tseem hu ua folic acid).

Vitamin deficiency twg ua rau tus kab mob pernicious Anaemia?

Txawm li cas los xij tsis muaj vitamin B-12 lossis tsis muaj folateua rau hom ntshav qab zib hu ua megaloblastic anemia (pernicious anemia). Nrog rau cov kab mob ntshav qab zib no, cov qe ntshav liab tsis zoo li qub.

Yuav ua li cas yog lub tshuab ntawm pernicious anemia?

Classic pernicious anemia yog tshwm sim los ntawm tsis ua haujlwm ntawm lub plab parietal hlwb kom tsim tau txausIF (ib lub plab protein secreted los ntawm parietal cells) tso cai rau kev nqus ntawm cov vitamin txaus txaus. B12.

Puas yog pernicious anemia yog kev tsis taus?

Yog tias koj raug kev txom nyem los ntawm pernicious anemia lossis subacute ua ke degeneration ntawm tus txha caj qaum, thiab nws cuam tshuam rau koj lub peev xwm ua haujlwm ntawm kev ua haujlwm, koj tuaj yeem tsim nyog tau txais Social Security tsis taus cov txiaj ntsig.

Pob B12 ntsiav tshuaj ua haujlwm rau pernicious anemia?

Rau kev kho mob mus sij hawm ntev, qhov ncauj hloov pauv vitamin B12 tuaj yeem ua tau zoo rau cov neeg mob uas muaj ntshav qab zib ntau. Cov neeg mob nyiam yuav tsum tau muab coj los xav txog hauv kev xaiv cov kev xaiv kho mob.

Cov tsos mob ntawm lub paj hlwb ntawm B12 deficiency yog dab tsi?

Kev tsis muaj vitamin B12 tuaj yeem ua rau muaj teeb meem hauv paj hlwb, uas cuam tshuam rau koj lub paj hlwb, xws li:

• pom teeb meem.
• memory poob.
• pins and needles (paraesthesia)
• poob ntawm lub cev sib koom ua ke (ataxia), uas tuaj yeem cuam tshuam koj lub cev tag nrho thiab ua rau nyuaj hais lus lossis taug kev.

Koj yuav tsum tau txhaj tshuaj B12 ntau npaum li cas rau kev mob ntshav qab zib?

For Pernicious Anemia

B12 yuav txhaj rau hauv cov leeg lossis hauv qab ntawm daim tawv nqaij ntawm 100 mcg txhua hnub rau ib lub lis piam, txhua hnub rau lwm lub lis piam, thiab tom qab ntawd txhua peb lossis plaub hnub rau ib hlis. Tom qab ntawd, 100 mcg yuav tsum tau txhaj ib hlis ib zaug rau lub neej.

Yuav ua li cas txhawb kev tso tawm ntawm qhov tseem ceeb?

qhov tseem ceeb yog tsim los ntawm lub plab parietal cell. Nws cov secretion yog stimulated los ntawm txhua txoj hauv kev paub los txhawb lub plab acid secretion: histamine, gastrin, thiab acetylcholine.

Kuv tuaj yeem nce kuv qhov kev xav tau li cas?

Txhawm rau nce cov vitamin B12 hauv koj cov zaub mov, noj ntau cov zaub mov uas muaj nws, xws li:

1. Ntses thiab plhaub ntses xws li trout, salmon, tuna ntses, thiab clams.
2. noj tshais cereal.
3. mis nyuj muaj roj tsawg, yogurt, thiab cheese.
4. Eggs.

Puas yog pernicious anemia thim rov qab?

Pernicious anemia yog ib qho yooj yim kho nrog cov tshuaj vitamin B12 lossis txhaj tshuaj nrog rau kev hloov pauv kev noj haus. Yuav tsum tau kho lub neej ntev. Cov teeb meem tshwm sim los ntawm kev kho tsis tau pernicious anemia tuaj yeem thim rov qab nrog kev kho mob.

Yuav ua li cas kho qhov tsis zoo ntawm tus kheej?

txhaj tshuaj vitamin B12.

YPuas vitamin B12 nce hemoglobin?

Kev nce ntxiv hauv hemoglobin tshwm sim los ntawm cov vitamin B tsawg heev ₁₂ concentration thiab mus txog kwv yees. 400 pg / mL, thaum hemoglobin tsis hloov pauv ntawm 700 pg / mL thiab txuas ntxiv mus. Vitamin B_{12 txhaj tshuaj tau siv los ntawm 34% ntawm cov neeg ncaws pob, ntau zaus los ntawm kev ua siab ntev tshaj li cov neeg ncaws pob muaj zog.}

Nws siv sijhawm ntev npaum li cas txhawm rau kho qhov tsis txaus B12?

Thaum koj pib kho koj qhov tsis txaus vitamin B12, nws tuaj yeem siv sijhawm txog rau rau rau 12 lub hlis kom rov zoo. Nws kuj yog ib qho uas tsis muaj kev txhim kho thaum thawj ob peb lub hlis ntawm kev kho mob.