T hlwb yog tsim nyob rau hauv the Thymus thiab tau programmed kom tshwj xeeb rau ib qho txawv teb chaws particle (antigen). Thaum lawv tawm ntawm cov thymus, lawv ncig thoob plaws lub cev kom txog thaum lawv paub txog lawv cov antigen nyob rau saum npoo ntawm antigen nthuav tawm cov hlwb (APCs).
T cells proliferate thiab mature nyob qhov twg?
T hlwb yog yug los ntawm hematopoietic qia hlwb, pom nyob rau hauv cov pob txha pob txha. Tsim cov T hlwb ces tsiv mus rau thymus qogkom paub tab. T hlwb muab lawv lub npe los ntawm lub cev no uas lawv loj hlob (los yog paub tab).
Pob T hlwb proliferate teb rau tus kab mob?
Piv txwv li, kab mob kisua rau clonal nthuav ntawm cov tshuaj tiv thaiv kab mob CD8 T hlwb, thaum lub sij hawm cov kab mob peripheral CD8 T hlwb loj heev thiab mus txog ~ 90% ntawm tag nrho CD8 T. cov hlwb yuav dhau los ua cov tshuaj tiv thaiv tshwj xeeb hauv cov kab mob lymphocytic choriomeningitis virus (7).
Puas T cells proliferate hauv cov qog ntshav?
Ua kom T hlwb muaj nyob hauv cov qog ntshav tuaj yeem txhawb nqa los ntawm cov tshuaj tiv thaiv kom sib faib, tsim cov nyhuv cytokines, thiab tsiv mus rau cov ntaub so ntswg peripheral. … Yog li ntawd, activated T cells tuaj yeem undergo clonal expansion hauv cov qog nqaij hlav, tab sis raug xaiv thiab khaws cia ua cov hlwb tsis sib faib hauv cov ntaub so ntswg nonlymphoid.
Kev loj hlob ntawm B thiab T hlwb tshwm sim nyob qhov twg?
Daim duab 9.11. Activated B cells tsim cov chaw tua kab mob hauv lymphoid follicles. Qee lub hlwb B tau qhib rau hauv thawj qhov kev tsom mus rau kev tsim cov kab mob hauv nruab nrab ntawm lub hauv paus follicle. Cov chaw Germinal yog qhov chaw ntawm B-cell proliferation sai thiab sib txawv.
