Ketogenesis yog qhov muaj zog tiv thaiv los ntawm insulin thiab txhawb nqa hauv cov xeev ntawm insulin tsis txaus thiab glucagon ntau dhau ((4), (6)).
insulin cuam tshuam li cas rau ketogenesis?
Nyob rau hauv daim siab insulin nce fatty acid synthesis thiab esterificationTib lub sijhawm malonyl-CoA tsim tau nce, uas inhibits acylcarnitine transferase system thiab yog li txo cov roj fatty acids. mus rau mitochondria thiab li no fatty acid oxidation thiab ketogenesis.
Y Puas insulin nce lossis txo qis ketogenesis?
Ketogenesis yog suav tias yog tswj los ntawm islet cov tshuaj hormones, insulin thiab glucagon (20). Insulin muaj zog tiv thaiv ketosis, feem ntau los ntawm kev txo lipolysis hauv adipocytes thiab txo cov khoom noj dawb fatty acids, lub substrate rau ketone lub cev tsim.
Y Yuav ua li cas insulin nres ketogenesis?
Insulin inhibits hormone-sensitive lipasethiab ua kom acetyl-CoA carboxylase, yog li txo qis cov khoom pib rau fatty acid oxidation thiab inhibiting lawv lub peev xwm nkag mus rau mitochondria.
YPuas ntshav qab zib ua rau ketogenesis?
Vim tias cov neeg mob ntshav qab zib hom 1 tsis muaj insulin, lawv tsis tuaj yeem metabolize ketones, uas maj mam ntws los ntawm cov zis hauv cov neeg tsis muaj tus kab mob. Rau cov neeg mob ntshav qab zib hom 1, ketosis tuaj yeem ua rau muaj ketone acids hauv lawv cov hlab ntshahu ua ntshav qab zib ketoacidosis (DKA), hais tias Dr.
