Kev hloov kho hauv lub ntiaj teb ntawm cov histones tuaj yeem ncaj qha cuam tshuam rau kev hloov pauv thiab nucleosome stability. … Zuag qhia tag nrho, kev ua haujlwm tsis ntev los no tau qhia tias cov kev hloov pauv tseem ceeb ntawm histone tuaj yeem tsis tsuas yog tswj hwm kev hloov pauv ncaj qha, tab sis tseem cuam tshuam cov txheej txheem xws li kho DNA, rov ua dua, stemness, thiab hloov pauv hauv lub xeev ntawm tes.
Puas hloov kho histone nce gene qhia?
Qhov tseem ceeb, histone methylation tuaj yeem ua rau lossis txo qis cov noob qhia, thiab yog li qhov cuam tshuam ntawm histone methylation ntawm cov noob qhia yog cov ntsiab lus tseem ceeb heev (Jenuwein thiab Allis 2001). Kev ua haujlwm lom neeg ntawm histone methylation yog qhov zoo tshaj plaws nyob rau hauv cov ntsiab lus ntawm histones H3 thiab H4 methylation.
Vim li cas kev hloov kho histone tseem ceeb hauv kev qhia noob?
Histones yog cov proteins uas sib xyaw thiab ntim DNA kom zoo rau hauv chromosomes. … Kev hloov kho ntawm histones yog ib qho tseem ceeb tom qab kev txhais cov txheej txheem uas ua lub luag haujlwm tseem ceeb hauv cov noob caj noob ces. Cov kev hloov kho cuam tshuam qhov kev qhia gene los ntawm kev hloov cov qauv ntawm chromatin lossis los ntawm kev nrhiav neeg ua haujlwm ntawm histone modifiers
Kev hloov pauv histone yog dab tsi?
Histone hloov kho yog ib qho ntawm cov txheej txheem tswj hwm uas hloov kho cov qauv chromatin thiab yog li cuam tshuam rau ntau yam DNA-templated txheej txheem, xws li cov noob hloov pauv, DNA replication, DNA recombination, thiab DNA kho hauv hlwb.
histones ua lub luag haujlwm li cas hauv kev tswj cov noob?
Histones tiv thaiv DNA los ntawm kev ua tangled thiab tiv thaiv nws ntawm DNA puasTsis tas li ntawd, histones ua lub luag haujlwm tseem ceeb hauv kev tswj cov noob thiab DNA replication. Yog tsis muaj histones, unwound DNA nyob rau hauv chromosomes yuav ntev heev. … Histones tej zaum yuav raug hloov kho los ntawm kev ua ntawm enzymes los tswj cov noob transcription.
