Sarin yog muaj zog inhibitor ntawm acetylcholinesterase, ib qho enzyme uas degrades cov neurotransmitter acetylcholine tom qab nws tso rau hauv lub synaptic cleft.
Yuav ua li cas hom inhibitor yog sarin?
Sarin yog ib qho muaj zog heev acetylcholinesterase (AchE) inhibitor nrog rau qhov tshwj xeeb thiab kev sib raug zoo rau cov enzyme. Kev tuag los ntawm sarin yog vim anoxia uas tshwm sim los ntawm txoj hlab pas txhaws, tsis muaj zog ntawm cov leeg ntawm kev ua pa, convulsions thiab ua pa tsis ua haujlwm.
Sarin cuam tshuam li cas ntawm acetylcholinesterase?
Sarin (GB, O-isopropyl methylphosphonofluoridate) yog lub zog organophosphorus (OP) cov paj hlwb uas inhibits acetylcholinesterase (AChE) irreversibly. Cov tom ntej ntawm acetylcholine (ACh) nyob rau hauv lub hauv paus paj hlwb (CNS) provokes qaug dab peg thiab, ntawm txaus koob, centrally-mediated ua pa nres
Puas paj hlwb puas yog agonist lossis antagonist?
Nws ua raws li tus antagonist rau muscarinicacetylcholine receptors, thaiv cov teebmeem ntawm acetylcholine ntau dhau. Qee cov tshuaj anticholinergics hluavtaws, xws li biperiden, tuaj yeem tiv thaiv cov tsos mob hauv nruab nrab ntawm cov paj hlwb ua rau lom tau zoo dua li atropine, vim tias lawv dhau los ntawm cov ntshav-hlwb hauv hlwb zoo dua li atropine.
Sarin siv rau dab tsi?
Sarin yog ib qho tshuaj lom neeg heev, siv hauv tshuaj riam phom thiab ua cov paj hlwb. Nws tau tshawb pom tab sis tsis siv hauv Tebchaws Yelemees thaum WWII. Cov tshuaj lom tuaj yeem ua rau tuag taus, comas, los ntshav, thiab xeev siab. Sarin yog ib qho tshuaj lom neeg heev uas siv los ua cov kab mob paj hlwb.
