Phenytoin metabolism yog koob tshuaj nyob ntawm. Kev tshem tawm ua raws li kev txiav txim thawj zaug kinetics (tsawg feem pua ntawm cov tshuaj metabolized nyob rau hauv ib lub sij hawm ib chav tsev) ntawm cov tshuaj tsis tshua muaj concentrations thiab zero-order kinetics (taag npaum li cas ntawm cov tshuaj metabolized ib chav tsev lub sij hawm) ntawm siab dua tshuaj concentration.
Puas phenytoin ua raws li saturation kinetics?
Phenytoin: Phenytoin nthuav tawm cim saturation ntawm cov metabolism hauv cov concentrations hauv kev kho mob ntau yam (10-20 mg / L) (Fig. 2). Yog li ntawd, kev siv tshuaj me me ua rau muaj kev nce ntxiv hauv tag nrho thiab tsis muaj zog hauv lub xeev cov tshuaj concentration.
Dab tsi tshuaj raug tshem tawm los ntawm xoom xaj kinetics?
Z
- Zero-Order Elimination Kinetics.
- Ziprasidone.
- Zispin.
- Zolpidem.
- Zonisamide.
- Zopiclone.
- Zotepine.
- Zuclopenthixol.
Yuav ua li cas cov tshuaj hauv qab no ua raws li xoom xaj kinetics?
Zero-order kinetics: Kev tshem tawm ntawm qhov tsis tu ncua ntawm cov tshuaj hauv ib chav tsev ntawm lub sijhawm ywj pheej ntawm qhov concentration ntawm cov tshuaj. Nrog ob peb yam tshuaj, xws li aspirin, ethanol, thiab phenytoin, cov koob tshuaj loj heev.
Dab tsi yog cov tshuaj xaj thawj zaug?
Thawj kev txiav txim kinetics tshwm sim thaum ib qho kev faib ua ntu zus ntawm cov tshuaj raug tshem tawm ib lub sijhawm. Kev txiav txim xoom: ib qho tshuaj tas li raug tshem tawm hauv ib lub sijhawm.
